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. 1998 Aug;74(874):486–489. doi: 10.1136/pgmj.74.874.486

Cytomegalovirus infection associated with ulcerative colitis in immunocompetent individuals.

C Rachima 1, E Maoz 1, S Apter 1, M Thaler 1, E Grossman 1, T Rosenthal 1
PMCID: PMC2360892  PMID: 9926125

Abstract

Gastrointestinal infection with cytomegalovirus (CMV) is usually found in immunocompromised patients and rarely affects immunocompetent subjects. We describe two immunocompetent patients who had primary CMV infection, and in both the disease was associated with ulcerative colitis. Both patients recovered from the CMV infection spontaneously.

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Selected References

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  1. Ayulo M., Aisner S. C., Margolis K., Moravec C. Cytomegalovirus-associated gastritis in a compromised host. JAMA. 1980 Apr 4;243(13):1364–1364. [PubMed] [Google Scholar]
  2. Balthazar E. J., Megibow A. J., Fazzini E., Opulencia J. F., Engel I. Cytomegalovirus colitis in AIDS: radiographic findings in 11 patients. Radiology. 1985 Jun;155(3):585–589. doi: 10.1148/radiology.155.3.2988010. [DOI] [PubMed] [Google Scholar]
  3. Berk T., Gordon S. J., Choi H. Y., Cooper H. S. Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease. Am J Gastroenterol. 1985 May;80(5):355–360. [PubMed] [Google Scholar]
  4. Bernades P., Nataf C., Ferchal F., Colimon R. Etude du taux des anticorps anticytomégalovirus chez des malades atteints de rectocolite hémorragique ou de maladie de Crohn. Etude coopérative du Groupe de Recherches sur les Entérocolites Cryptogénétiques (GREC). Gastroenterol Clin Biol. 1980 Feb;4(2):128–133. [PubMed] [Google Scholar]
  5. Buckner F. S., Pomeroy C. Cytomegalovirus disease of the gastrointestinal tract in patients without AIDS. Clin Infect Dis. 1993 Oct;17(4):644–656. doi: 10.1093/clinids/17.4.644. [DOI] [PubMed] [Google Scholar]
  6. Cooper H. S., Raffensperger E. C., Jonas L., Fitts W. T., Jr Cytomegalovirus inclusions in patients with ulcerative colitis and toxic dilation requiring colonic resection. Gastroenterology. 1977 Jun;72(6):1253–1256. [PubMed] [Google Scholar]
  7. Cunningham M., Cantoni L., Humair L. Cytomegalovirus primo-infection in a patient with idiopathic proctitis. Am J Gastroenterol. 1986 Jul;81(7):586–588. [PubMed] [Google Scholar]
  8. Dent D. M., Duys P. J., Bird A. R., Birkenstock W. E. Cytomegalic virus infection of bowel in adults. S Afr Med J. 1975 Apr 12;49(16):669–672. [PubMed] [Google Scholar]
  9. Diepersloot R. J., Kroes A. C., Visser W., Jiwa N. M., Rothbarth P. H. Acute ulcerative proctocolitis associated with primary cytomegalovirus infection. Arch Intern Med. 1990 Aug;150(8):1749–1751. [PubMed] [Google Scholar]
  10. Drew W. L., Mintz L., Miner R. C., Sands M., Ketterer B. Prevalence of cytomegalovirus infection in homosexual men. J Infect Dis. 1981 Feb;143(2):188–192. doi: 10.1093/infdis/143.2.188. [DOI] [PubMed] [Google Scholar]
  11. Farmer G. W., Vincent M. M., Fuccillo D. A., Horta-Barbosa L., Ritman S., Sever J. L., Gitnick G. L. Viral investigations in ulcerative colitis and regional enteritis. Gastroenterology. 1973 Jul;65(1):8–18. [PubMed] [Google Scholar]
  12. Gertler S. L., Pressman J., Price P., Brozinsky S., Miyai K. Gastrointestinal cytomegalovirus infection in a homosexual man with severe acquired immunodeficiency syndrome. Gastroenterology. 1983 Dec;85(6):1403–1406. [PubMed] [Google Scholar]
  13. Goodgame R. W. Gastrointestinal cytomegalovirus disease. Ann Intern Med. 1993 Nov 1;119(9):924–935. doi: 10.7326/0003-4819-119-9-199311010-00010. [DOI] [PubMed] [Google Scholar]
  14. Guttman D., Raymond A., Gelb A., Ehya H., Mather U., Mildvan D., Spigland I. Virus-associated colitis in homosexual men: two case reports. Am J Gastroenterol. 1983 Mar;78(3):167–169. [PubMed] [Google Scholar]
  15. Henson D. Cytomegalovirus inclusion bodies in the gastrointestinal tract. Arch Pathol. 1972 Jun;93(6):477–482. [PubMed] [Google Scholar]
  16. Keren D. F., Milligan F. D., Strandberg J. D., Yardley J. H. Intercurrent cytomegalovirus colitis in a patient with ulcerative colitis. Johns Hopkins Med J. 1975 Apr;136(4):178–182. [PubMed] [Google Scholar]
  17. LEVINE R. S., WARNER N. E., JOHNSON C. F. CYTOMEGALIC INCLUSION DISEASE IN THE GASTRO-INTESTINAL TRACT OF ADULTS. Ann Surg. 1964 Jan;159:37–48. doi: 10.1097/00000658-196401000-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Miller M. J., Bovey S., Pado K., Bruckner D. A., Wagar E. A. Application of PCR to multiple specimen types for diagnosis of cytomegalovirus infection: comparison with cell culture and shell vial assay. J Clin Microbiol. 1994 Jan;32(1):5–10. doi: 10.1128/jcm.32.1.5-10.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Orloff J. J., Saito R., Lasky S., Dave H. Toxic megacolon in cytomegalovirus colitis. Am J Gastroenterol. 1989 Jul;84(7):794–797. [PubMed] [Google Scholar]
  20. Orvar K., Murray J., Carmen G., Conklin J. Cytomegalovirus infection associated with onset of inflammatory bowel disease. Dig Dis Sci. 1993 Dec;38(12):2307–2310. doi: 10.1007/BF01299914. [DOI] [PubMed] [Google Scholar]
  21. POWELL R. D., WARNER N. E., LEVINE R. S., KIRSNER J. B. Cytomegalic inclusion disease and ulcerative colitis; report of a case in a young adult. Am J Med. 1961 Feb;30:334–340. doi: 10.1016/0002-9343(61)90105-x. [DOI] [PubMed] [Google Scholar]
  22. Phipps P. H., Grégoire L., Rossier E., Perry E. Comparison of five methods of cytomegalovirus antibody screening of blood donors. J Clin Microbiol. 1983 Dec;18(6):1296–1300. doi: 10.1128/jcm.18.6.1296-1300.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Quinnan G. V., Jr, Masur H., Rook A. H., Armstrong G., Frederick W. R., Epstein J., Manischewitz J. F., Macher A. M., Jackson L., Ames J. Herpesvirus infections in the acquired immune deficiency syndrome. JAMA. 1984 Jul 6;252(1):72–77. [PubMed] [Google Scholar]
  24. Rubin R. H. Impact of cytomegalovirus infection on organ transplant recipients. Rev Infect Dis. 1990 Sep-Oct;12 (Suppl 7):S754–S766. doi: 10.1093/clinids/12.supplement_7.s754. [DOI] [PubMed] [Google Scholar]
  25. Schmitz H., Doerr H. W., Kampa D., Vogt A. Solid-phase enzyme immunoassay for immunoglobulin M antibodies to cytomegalovirus. J Clin Microbiol. 1977 Jun;5(6):629–634. doi: 10.1128/jcm.5.6.629-634.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Schooley R. T. Cytomegalovirus in the setting of infection with human immunodeficiency virus. Rev Infect Dis. 1990 Sep-Oct;12 (Suppl 7):S811–S819. doi: 10.1093/clinids/12.supplement_7.s811. [DOI] [PubMed] [Google Scholar]
  27. Scullard G. H., Smith C. I., Merigan T. C., Robinson W. S., Gregory P. B. Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B. Gastroenterology. 1981 Dec;81(6):987–991. [PubMed] [Google Scholar]
  28. Sidi S., Graham J. H., Razvi S. A., Banks P. A. Cytomegalovirus infection of the colon associated with ulcerative colitis. Arch Surg. 1979 Jul;114(7):857–859. doi: 10.1001/archsurg.1979.01370310099019. [DOI] [PubMed] [Google Scholar]
  29. Spencer G. D., Hackman R. C., McDonald G. B., Amos D. E., Cunningham B. A., Meyers J. D., Thomas E. D. A prospective study of unexplained nausea and vomiting after marrow transplantation. Transplantation. 1986 Dec;42(6):602–607. doi: 10.1097/00007890-198612000-00006. [DOI] [PubMed] [Google Scholar]
  30. Surawicz C. M., Myerson D. Self-limited cytomegalovirus colitis in immunocompetent individuals. Gastroenterology. 1988 Jan;94(1):194–199. doi: 10.1016/0016-5085(88)90630-0. [DOI] [PubMed] [Google Scholar]
  31. Swarbrick E. T., Kingham J. G., Price H. L., Blackshaw A. J., Griffiths P. D., Darougar S., Buckell N. A. Chlamydia, cytomegalovirus, and Yersinia in inflammatory bowel disease. Lancet. 1979 Jul 7;2(8132):11–12. doi: 10.1016/s0140-6736(79)90176-4. [DOI] [PubMed] [Google Scholar]
  32. WONG T. W., WARNER N. E. Cytomegalic inclusion disease in adults. Report of 14 cases with review of literature. Arch Pathol. 1962 Nov;74:403–422. [PubMed] [Google Scholar]

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