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. 1998 Jun;74(872):365–366. doi: 10.1136/pgmj.74.872.365

Vitamin D replacement in Asians with diabetes may increase insulin resistance.

A V Taylor 1, P H Wise 1
PMCID: PMC2360945  PMID: 9799895

Abstract

We report three cases of vitamin D replacement in British Asians with vitamin D deficiency and non-insulin-dependent diabetes mellitus. In all cases, replacement resulted in an increase in insulin resistance and a deterioration of glycaemic control.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bansal S., Rizvi S. N., Rao M. B., Vaishnava H. Effect of hypocalcaemia on glucose tolerance, insulin release and free fatty acid levels in human subjects. Postgrad Med J. 1975 Jul;51(597):471–475. doi: 10.1136/pgmj.51.597.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Beaulieu C., Kestekian R., Havrankova J., Gascon-Barré M. Calcium is essential in normalizing intolerance to glucose that accompanies vitamin D depletion in vivo. Diabetes. 1993 Jan;42(1):35–43. doi: 10.2337/diab.42.1.35. [DOI] [PubMed] [Google Scholar]
  3. Boucher B. J., Mannan N., Noonan K., Hales C. N., Evans S. J. Glucose intolerance and impairment of insulin secretion in relation to vitamin D deficiency in east London Asians. Diabetologia. 1995 Oct;38(10):1239–1245. doi: 10.1007/BF00422375. [DOI] [PubMed] [Google Scholar]
  4. Boucher B. J. Strategies for reduction in the prevalence of NIDDM; the case for a population-based approach to the development of policies to deal with environmental factors in its aetiology. Diabetologia. 1995 Sep;38(9):1125–1129. doi: 10.1007/BF00402186. [DOI] [PubMed] [Google Scholar]
  5. Després J. P., Lamarche B., Mauriège P., Cantin B., Dagenais G. R., Moorjani S., Lupien P. J. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med. 1996 Apr 11;334(15):952–957. doi: 10.1056/NEJM199604113341504. [DOI] [PubMed] [Google Scholar]
  6. Duncan M. H., Singh B. M., Wise P. H., Carter G., Alaghband-Zadeh J. A simple measure of insulin resistance. Lancet. 1995 Jul 8;346(8967):120–121. doi: 10.1016/s0140-6736(95)92143-5. [DOI] [PubMed] [Google Scholar]
  7. Finch P. J., Ang L., Eastwood J. B., Maxwell J. D. Clinical and histological spectrum of osteomalacia among Asians in south London. Q J Med. 1992 Jun;83(302):439–448. [PubMed] [Google Scholar]
  8. Gedik O., Akalin S. Effects of vitamin D deficiency and repletion on insulin and glucagon secretion in man. Diabetologia. 1986 Mar;29(3):142–145. doi: 10.1007/BF02427083. [DOI] [PubMed] [Google Scholar]
  9. Henderson J. B., Dunnigan M. G., McIntosh W. B., Abdul Motaal A., Hole D. Asian osteomalacia is determined by dietary factors when exposure to ultraviolet radiation is restricted: a risk factor model. Q J Med. 1990 Sep;76(281):923–933. [PubMed] [Google Scholar]
  10. Kocián J. Diabetické osteopatie. Príznivý vliv lécby osteomalacie vitaminem D a vápníkem na výsi glykémie. Vnitr Lek. 1992 Apr;38(4):352–356. [PubMed] [Google Scholar]
  11. Kumar S., Davies M., Zakaria Y., Mawer E. B., Gordon C., Olukoga A. O., Boulton A. J. Improvement in glucose tolerance and beta-cell function in a patient with vitamin D deficiency during treatment with vitamin D. Postgrad Med J. 1994 Jun;70(824):440–443. doi: 10.1136/pgmj.70.824.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Orwoll E., Riddle M., Prince M. Effects of vitamin D on insulin and glucagon secretion in non-insulin-dependent diabetes mellitus. Am J Clin Nutr. 1994 May;59(5):1083–1087. doi: 10.1093/ajcn/59.5.1083. [DOI] [PubMed] [Google Scholar]

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