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. 1976 Feb;125(2):540–544. doi: 10.1128/jb.125.2.540-544.1976

Evidence for the involvement of ribonucleic acid in the production of F pili.

P Fives-Taylor, C P Novotny
PMCID: PMC236113  PMID: 1107325

Abstract

The effects of rifampin and streptolydigin, inhibitors of ribonucleic acid (RNA) synthesis, on the production of F pili by Escherichia coli were studied by electron microscopy. The inhibition of RNA synthesis reduces the number of new pili produced by depiliated cells, but does not affect their length or the number of pili present at the time of inhibition or the retraction of pili. We suggest that the rifampin-sensitive step may be linked to the establishement of a site for pili production. Evidence is provided that chloramphenicol inhibits retraction. We suggest that retraction requires some protein whose pool size is limited.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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