Abstract
Pantothenate is required for the formation of filaments by Erwinia carotovora. This has been demonstrated for the following division-inhibiting agents: D-serine, D-cycloserine, penicillin, vancomycin, fluoride ion, and ultraviolet light. D-Serine inhibits pantothenate synthesis in an ammonia-glucose or an ammonia-pyruvate medium; therefore, it is necessary to add pantothenate to obtain filament formation in these media, using D-serine as the division-inhibiting agent. Under conditions in which pantothenate synthesis is not inhibited by the agent producing filaments, the need for it for filamentation was shown by the use of salicylate, an inhibitor of endogenous pantothenate synthesis. Evidence is presented that the production of filaments is a specific response to pantothenate, rather than a nonspecific growth stimulation.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Das D. N., Toennies G. A versatile buffered scintillation system. Anal Biochem. 1968 Apr;23(1):26–34. doi: 10.1016/0003-2697(68)90005-5. [DOI] [PubMed] [Google Scholar]
- Das D. N., Toennies G. Relations between coenzyme A and presumptive acyl carrier protein in different conditions of streptococcal growth. J Bacteriol. 1969 Jun;98(3):898–902. doi: 10.1128/jb.98.3.898-902.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GRULA E. A. Cell division in a species of Erwinia. I. Inhibition of division by D-amino acids. J Bacteriol. 1960 Sep;80:375–385. doi: 10.1128/jb.80.3.375-385.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GRULA E. A., GRULA M. M. Cell division in a species of Erwinia III. Reversal of inhibition of cell division caused by D-amino acids, penicillin, and ultraviolet light. J Bacteriol. 1962 May;83:981–988. doi: 10.1128/jb.83.5.981-988.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GRULA M. M., GRULA E. A. Cell division in a species of Erwinia IV. Metabolic blocks in panothenate biosynthesis and their relationship to inhibition of cell division. J Bacteriol. 1962 May;83:989–997. doi: 10.1128/jb.83.5.989-997.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Grula M. M., Smith R. W., Parham C. F., Grula E. A. Cell division in a species of Erwinia. XI. Some aspects of the carbon and nitrogen nutrition of Erwinia species. Can J Microbiol. 1968 Nov;14(11):1217–1224. doi: 10.1139/m68-204. [DOI] [PubMed] [Google Scholar]
- Grula M. M., Smith R. W., Parham C. F., Grula E. A. Cell division in a species of Erwinia. XII. A study of nutritional influences in D-serine inhibition of growth and division of Erwinia sp., and of certain specific sites of D-serine action. Can J Microbiol. 1968 Nov;14(11):1225–1238. doi: 10.1139/m68-205. [DOI] [PubMed] [Google Scholar]
- HOWARD-FLANDERS P., SIMSON E., THERIOT L. A LOCUS THAT CONTROLS FILAMENT FORMATION AND SENSITIVITY TO RADIATION IN ESCHERICHIA COLI K-12. Genetics. 1964 Feb;49:237–246. doi: 10.1093/genetics/49.2.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MAAS W. K. Pantothenate studies, II. Evidence from Mutants for interference by salicylate with pantoate synthesis. J Bacteriol. 1952 Feb;63(2):227–232. doi: 10.1128/jb.63.2.227-232.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slater M., Schaechter M. Control of cell division in bacteria. Bacteriol Rev. 1974 Jun;38(2):199–221. doi: 10.1128/br.38.2.199-221.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Starr M. P., Chatterjee A. K. The genus Erwinia: enterobacteria pathogenic to plants and animals. Annu Rev Microbiol. 1972;26:389–426. doi: 10.1146/annurev.mi.26.100172.002133. [DOI] [PubMed] [Google Scholar]
- Walker J. R., Shafiq N. A., Allen R. G. Bacterial cell division regulation: physiological effects of crystal violet on Escherichia coli lon + and lon - strains. J Bacteriol. 1971 Dec;108(3):1296–1303. doi: 10.1128/jb.108.3.1296-1303.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]