Abstract
The incidence of unilateral, but not bilateral, retinoblastoma in human populations at different geographical locations increases significantly with ambient erythemal dose of ultraviolet B radiation from sunlight. This supports the hypothesis that sunlight plays a role in retinoblastoma formation. © 1999 Cancer Research Campaign
Keywords: retinoblastoma, epidemiology, sunlight, ultraviolet radiation
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Selected References
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- Knudson A. G., Jr Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971 Apr;68(4):820–823. doi: 10.1073/pnas.68.4.820. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Newton R., Ferlay J., Reeves G., Beral V., Parkin D. M. Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye. Lancet. 1996 May 25;347(9013):1450–1451. doi: 10.1016/s0140-6736(96)91685-2. [DOI] [PubMed] [Google Scholar]