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. 1999 May 1;80(3-4):403–406. doi: 10.1038/sj.bjc.6690370

Conservative treatment followed by chemotherapy with doxorubicin and ifosfamide for cervical sarcoma botryoides in young females

G Zanetta 1, S M Rota 1, A Lissoni 1, S Chiari 1, G Bratina 2, C Mangioni 1
PMCID: PMC2362332  PMID: 10408845

Abstract

Sarcoma botryoides of the cervix is an extremely rare tumour and seems to be associated with a better prognosis than its vaginal counterpart. Recent studies have suggested that it is possible to limit surgery to local excision in stage I cases. We report three cases of young subjects treated successfully with polypectomy or diathermy loop excision followed by adjuvant chemotherapy. One patient had a local recurrence which was treated with further local excision. All subjects remain alive without evidence of recurrence and with normal menstrual function 36, 38 and 38 months following initial diagnosis. A conservative surgical approach to early cervical sarcoma botryoides is possible. The efficacy of adjuvant chemotherapy and the regimen of choice still need to be investigated. © 1999 Cancer Research Campaign

Keywords: sarcoma botryoides, embryonal rhabdomyosarcoma, cervix, chemotherapy, conservative surgery

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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