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British Journal of Cancer logoLink to British Journal of Cancer
. 1999 Feb;79(3-4):655–657. doi: 10.1038/sj.bjc.6690103

Evidence of space–time clustering of childhood acute lymphoblastic leukaemia in Sweden

B Gustafsson 1, J Carstensen 2,3
PMCID: PMC2362409  PMID: 10027345

Abstract

We have examined 645 recorded cases of childhood acute lymphatic leukaemia (ALL) in Sweden during 1973–89 to identify space–time clustering by using the close-pair method of Knox. The records included date of birth and of diagnosis as well as addresses at birth and at diagnosis. There was a significant excess of case pairs close in date of birth and place of birth in the 5- to 15-year age group. © 1999 Cancer Research Campaign

Keywords: childhood acute lymphatic leukaemia, space–time clustering, viral hypothesis

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