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. 1999 Jun;80(7):1103–1106. doi: 10.1038/sj.bjc.6690471

Human herpes virus-6 seroprevalence and leukaemias: a case-control study

G Gentile 1, A Mele 2, G Ragona 3,4, A Faggioni 3, C Zompetta 3, M E Tosti 2, G Visani 5, G Castelli 6, A Pulsoni 1, B Monarca 1, P Martino 1, F Mandelli 1; G I M E M A (Gruppo Italiano Malattie Ematologiiche dell' Adulto)1
PMCID: PMC2363056  PMID: 10362124

Abstract

The relationships between acute myeloid leukaemia (AML), acute lymphocytic leukaemia (ALL), chronic myeloid leukaemia (CML) and refractory anaemia with excess of blasts (RAEB) and human herpes virus (HHV)-6 antibody level were investigated in a multicentre case-control study. An association between increased HHV-6 seropositivity and geometric mean titre ratio with AML was shown: P for trend = 0.022, adjusted odds ratio 1.20, 95% confidence interval 1.07–1.33 respectively. No association was found between HHV-6 and ALL, CML or RAEB. © 1999 Cancer Research Campaign

Keywords: HHV-6, leukaemia, viral aetiology

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Footnotes

The members of GIMEMA are as follows: R Colombini (Istituto di Ematologia Seragnoli, Bologna); S Merante (Divisione di Ematologia, Pavia); A Capobianchi, S Capucci, A Vitale (Dipartimento di Biotecnologie Cellulari e Ematologia, Roma)

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

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