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. 2000 Jun;82(11):1892–1894. doi: 10.1054/bjoc.1999.1212

Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese

H Saeki 1, S Ohno 1, K Araki 1, A Egashira 1, H Kawaguchi 1, Y Ikeda 1, M Morita 1, K Kitamura 1, K Sugimachi 1
PMCID: PMC2363236  PMID: 10839309

Abstract

We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation. © 2000 Cancer Research Campaign

Keywords: alcohol, cigarettes, p53, oesophageal squamous cell carcinoma

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Selected References

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