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British Journal of Cancer logoLink to British Journal of Cancer
. 2000 Jan 18;82(3):535–537. doi: 10.1054/bjoc.1999.0959

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

M Palicio 1, I Blanco 2, S Tórtola 3, I González 3, E Marcuello 4, J Brunet 4, F Lluis 1, J J González-Aguilera 5, M A Peinado 3, G Capella 1,6
PMCID: PMC2363304  PMID: 10682661

Abstract

A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function. © 2000 Cancer Research Campaign

Keywords: polymorphism, colorectal neoplasm, familial, Spain

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Selected References

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