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British Journal of Cancer logoLink to British Journal of Cancer
letter
. 2000 Nov;83(9):1234–1237. doi: 10.1054/bjoc.2000.1467

Endocrine correlates of male breast cancer risk: a case-control study in Athens, Greece

E Petridou 1,2, G Giokas 2, H Kuper 1, L A Mucci 1, D Trichopoulos 1,2
PMCID: PMC2363586  PMID: 11027439

Abstract

We studied the relation of certain endocrine-related variables among 23 cases of male breast cancer and 76 apparently healthy male controls. There were significant inverse associations with smoking (P = 0.03), birth order (P = 0.02) and reported frequency of orgasms in later life (P = 0.0004). The study provides strong indirect evidence that endocrine factors are important in the aetiology of male breast cancer. © 2000 Cancer Research Campaign

Keywords: male breast cancer, smoking, birth order, endocrine factors

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