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British Journal of Cancer logoLink to British Journal of Cancer
letter
. 2001 Jun;84(11):1460–1462. doi: 10.1054/bjoc.2001.1799

Childhood cancer incidence in a cohort of twin babies

M F G Murphy 1, D Whiteman 1, K Hey 1, M Griffith 2, L Gill 2, M J Goldacre 2, T J Vincent 3, K Bunch 3
PMCID: PMC2363658  PMID: 11384093

Abstract

We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39–120). Pooled analysis with data from published cohort studies indicates a similar significant incidence reduction (SIR 81, 95% CI 67–96). Further studies are warranted. © 2001 Cancer Research Campaign http://www.bjcancer.com

Keywords: twins, childhood cancer, childhood mortality

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