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British Journal of Cancer logoLink to British Journal of Cancer
letter
. 2001 Aug;85(3):337–340. doi: 10.1054/bjoc.2001.1903

Haemophilus influenzae type b serology in childhood leukaemia: A case–control study

F D Groves 1,2, D Sinha 1, H Kayhty 3, J J Goedert 4, P H Levine 4
PMCID: PMC2364071  PMID: 11487261

Abstract

Antibody to Haemophilus influenzae type b (Hib) polysaccharide (PRP) was measured in 42 children with acute lymphoblastic leukaemia (ALL) and 42 non-leukaemic hospital controls. Modelling anti-PRP concentrations as a function of age revealed that the slopes of the trend lines differed significantly between cases and controls (P = 0.05); anti-PRP concentrations were lower among younger cases, and higher among older cases, than among controls of the same ages. © 2001 Cancer Research Campaign http://www.bjcancer.com

Keywords: leukaemia, child, serology, Haemophilus influenzae type b, case–control study

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