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. 2001 Aug;85(4):497–503. doi: 10.1054/bjoc.2001.1965

Pain and health-related quality of life in a geographically defined population of men with prostate cancer

G Sandblom 1, P Carlsson 2, P Sigsjö 2, E Varenhorst 1
PMCID: PMC2364104  PMID: 11506486

Abstract

In order to provide baseline data on pain and health-related quality of life, to explore factors predicting pain and reduced quality of life, and to find potentially undertreated cases in men with prostate cancer, we undertook a population-based questionnaire study. The questionnaire, which included the EuroQo1 instrument, the Brief Pain Inventory form and 8 specially designed questions, was sent to all men with prostate cancer in the county of Östergötland, Sweden. Of the 1442 men included in the study, 1243 responded to the questionnaire. Altogether 42% had perceived pain during the previous week and 26% stated their quality of life to be 50% or lower on a visual analogue scale. A high rating of health care availability and short time since diagnosis were found to significantly predict lower ratings of pain (P< 0.05). Pain was found to be a significant predictive factor for decreased quality of life together with high age, low rating of health care availability and palliative treatment (P< 0.05). In conclusion, assessment and treatment of pain is essential for a good quality of life in men with prostate cancer. The monitoring of prostate cancer patients should be individualized to fit the demands of the groups with the greatest need for support. © 2001 Cancer Research Campaign http://www.bjcancer.com

Keywords: pain measurement; pain; quality of life; registries; prostatic neoplasms, health services accessibility

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Selected References

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  1. Brooks R. G., Jendteg S., Lindgren B., Persson U., Björk S. EuroQol: health-related quality of life measurement. Results of the Swedish questionnaire exercise. Health Policy. 1991 Jun;18(1):37–48. doi: 10.1016/0168-8510(91)90142-k. [DOI] [PubMed] [Google Scholar]
  2. Cleary P. D., Morrissey G., Oster G. Health-related quality of life in patients with advanced prostate cancer: a multinational perspective. Qual Life Res. 1995 Jun;4(3):207–220. doi: 10.1007/BF02260860. [DOI] [PubMed] [Google Scholar]
  3. Cleeland C. S., Gonin R., Hatfield A. K., Edmonson J. H., Blum R. H., Stewart J. A., Pandya K. J. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med. 1994 Mar 3;330(9):592–596. doi: 10.1056/NEJM199403033300902. [DOI] [PubMed] [Google Scholar]
  4. Cleeland C. S., Nakamura Y., Mendoza T. R., Edwards K. R., Douglas J., Serlin R. C. Dimensions of the impact of cancer pain in a four country sample: new information from multidimensional scaling. Pain. 1996 Oct;67(2-3):267–273. doi: 10.1016/0304-3959(96)03131-4. [DOI] [PubMed] [Google Scholar]
  5. Cleeland C. S., Ryan K. M. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994 Mar;23(2):129–138. [PubMed] [Google Scholar]
  6. Curran D., Fossa S., Aaronson N., Kiebert G., Keuppens F., Hall R., Keuppens E. Baseline quality of life of patients with advanced prostate cancer. European Organization for Research and Treatment of Cancer (EORTC), Genito-Urinary Tract Cancer Cooperative Group (GUT-CCG) Eur J Cancer. 1997 Oct;33(11):1809–1814. doi: 10.1016/s0959-8049(97)00187-1. [DOI] [PubMed] [Google Scholar]
  7. Elliott A. M., Smith B. H., Penny K. I., Smith W. C., Chambers W. A. The epidemiology of chronic pain in the community. Lancet. 1999 Oct 9;354(9186):1248–1252. doi: 10.1016/s0140-6736(99)03057-3. [DOI] [PubMed] [Google Scholar]
  8. Fowler F. J., Jr, Barry M. J., Lu-Yao G., Wasson J., Roman A., Wennberg J. Effect of radical prostatectomy for prostate cancer on patient quality of life: results from a Medicare survey. Urology. 1995 Jun;45(6):1007–1015. doi: 10.1016/s0090-4295(99)80122-8. [DOI] [PubMed] [Google Scholar]
  9. Greenwald H. P., Bonica J. J., Bergner M. The prevalence of pain in four cancers. Cancer. 1987 Nov 15;60(10):2563–2569. doi: 10.1002/1097-0142(19871115)60:10<2563::aid-cncr2820601036>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  10. Helgesen F., Andersson S. O., Gustafsson O., Varenhorst E., Gobén B., Carnock S., Sehlstedt L., Carlsson P., Holmberg L., Johansson J. E. Follow-up of prostate cancer patients by on-demand contacts with a specialist nurse: a randomized study. Scand J Urol Nephrol. 2000 Feb;34(1):55–61. doi: 10.1080/003655900750016904. [DOI] [PubMed] [Google Scholar]
  11. Jønler M., Nielsen O. S., Wolf H. Urinary symptoms, potency, and quality of life in patients with localized prostate cancer followed up with deferred treatment. Urology. 1998 Dec;52(6):1055–1063. doi: 10.1016/s0090-4295(98)00449-x. [DOI] [PubMed] [Google Scholar]
  12. Krupski T., Petroni G. R., Bissonette E. A., Theodorescu D. Quality-of-life comparison of radical prostatectomy and interstitial brachytherapy in the treatment of clinically localized prostate cancer. Urology. 2000 May;55(5):736–742. doi: 10.1016/s0090-4295(99)00597-x. [DOI] [PubMed] [Google Scholar]
  13. Larue F., Colleau S. M., Brasseur L., Cleeland C. S. Multicentre study of cancer pain and its treatment in France. BMJ. 1995 Apr 22;310(6986):1034–1037. doi: 10.1136/bmj.310.6986.1034. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lubeck D. P., Litwin M. S., Henning J. M., Stoddard M. L., Flanders S. C., Carroll P. R. Changes in health-related quality of life in the first year after treatment for prostate cancer: results from CaPSURE. Urology. 1999 Jan;53(1):180–186. doi: 10.1016/s0090-4295(98)00408-7. [DOI] [PubMed] [Google Scholar]
  15. Mandelblatt J. S., Yabroff K. R., Kerner J. F. Equitable access to cancer services: A review of barriers to quality care. Cancer. 1999 Dec 1;86(11):2378–2390. [PubMed] [Google Scholar]
  16. Portenoy R. K., Lesage P. Management of cancer pain. Lancet. 1999 May 15;353(9165):1695–1700. doi: 10.1016/S0140-6736(99)01310-0. [DOI] [PubMed] [Google Scholar]
  17. Rosendahl I., Kiebert G. M., Curran D., Cole B. F., Weeks J. C., Denis L. J., Hall R. R. Quality-adjusted survival (Q-TWiST) analysis of EORTC trial 30853: comparing goserelin acetate and flutamide with bilateral orchiectomy in patients with metastatic prostate cancer. European Organization for Research and Treatment of Cancer. Prostate. 1999 Feb 1;38(2):100–109. doi: 10.1002/(sici)1097-0045(19990201)38:2<100::aid-pros3>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]
  18. Sandblom G., Dufmats M., Nordenskjöld K., Varenhorst E. Prostate carcinoma trends in three counties in Sweden 1987-1996: results from a population-based national cancer register. South-East Region Prostate Cancer Group. Cancer. 2000 Mar 15;88(6):1445–1453. doi: 10.1002/(sici)1097-0142(20000315)88:6<1445::aid-cncr24>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  19. Serlin R. C., Mendoza T. R., Nakamura Y., Edwards K. R., Cleeland C. S. When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain. 1995 May;61(2):277–284. doi: 10.1016/0304-3959(94)00178-H. [DOI] [PubMed] [Google Scholar]
  20. Smith D. S., Carvalhal G. F., Schneider K., Krygiel J., Yan Y., Catalona W. J. Quality-of-life outcomes for men with prostate carcinoma detected by screening. Cancer. 2000 Mar 15;88(6):1454–1463. [PubMed] [Google Scholar]
  21. Wang X. S., Cleeland C. S., Mendoza T. R., Engstrom M. C., Liu S., Xu G., Hao X., Wang Y., Ren X. S. The effects of pain severity on health-related quality of life: a study of Chinese cancer patients. Cancer. 1999 Nov 1;86(9):1848–1855. [PubMed] [Google Scholar]
  22. van Agt H. M., Essink-Bot M. L., Krabbe P. F., Bonsel G. J. Test-retest reliability of health state valuations collected with the EuroQol questionnaire. Soc Sci Med. 1994 Dec;39(11):1537–1544. doi: 10.1016/0277-9536(94)90005-1. [DOI] [PubMed] [Google Scholar]

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