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. 1994;2(3):115–119. doi: 10.1155/S1064744994000499

Comparison of Culture and Rapid Enzyme Immunoassay for the Detection of Group B Streptococcus in High-Risk Pregnancies

Mara J Dinsmoor 1,✉, Harry P Dalton 1, Thomas C C Peng 1, James T Christmas 1, Sousan Sayahtaheri-Altaie 1, Kevin Harvey 1, J Peter VanDorsten 1
PMCID: PMC2364376  PMID: 18475376

Abstract

Objective: The purpose of this study was to evaluate the Equate Strep B® test for clinical use in patients at high risk for complications from group B streptococcus (GBS) disease.

Methods: Vaginoperineal swabs were obtained from patients with preterm premature rupture of the membranes and/or preterm labor and semiquantitative GBS cultures and Equate® assay were performed.

Results: From May 14, 1990, to April 30, 1992, 650 patients were enrolled; 626 had both culture and Equate® results available, of whom 24% were colonized with GBS. The sensitivity, specificity, positive predictive value, and negative predictive value of the rapid assay were 28%, 84%, 35%, and 79%, respectively. Although the prevalence of GBS was higher in patients with ruptured membranes compared with those with intact membranes, rupture of membranes did not affect test sensitivity or specificity.

Conclusions: We conclude that the Equate® rapid assay is not a sensitive method of GBS detection in high-risk patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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