Abstract
Objective: We prospectively evaluated the rate of adverse reproductive outcomes following pelvic inflammatory disease (PID) in a small cohort of American women.
Methods: We enrolled 28 patients having either salpingitis confirmed by laparoscopy or endometritis confirmed by endometrial biopsy. The follow-up was maintained by clinic visits and telephone contact.
Results: A median of 15.4 months of follow-up was accomplished for 82.1% of these women. Fifty-two percent (13/25) had unprotected sexual activity without conception for at least 6 months. Fully 55.6% (10/18) of the cohort were involuntarily infertile after at least 1 year of follow-up.
Conclusion: In the first prospective cohort study of the reproductive outcomes of American women having had PID, high rates of infertility at 1 year of follow-up were experienced by these women.
Full Text
The Full Text of this article is available as a PDF (338.0 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aral S. O., Mosher W. D., Cates W., Jr Self-reported pelvic inflammatory disease in the United States, 1988. JAMA. 1991 Nov 13;266(18):2570–2573. [PubMed] [Google Scholar]
- Brihmer C., Brundin J. Second look laparoscopy after treatment of acute salpingitis with doxycycline/benzylpenicillin procaine or trimethoprim-sulfamethoxazole. Scand J Infect Dis Suppl. 1988;53:65–69. [PubMed] [Google Scholar]
- Brunham R. C., Binns B., Guijon F., Danforth D., Kosseim M. L., Rand F., McDowell J., Rayner E. Etiology and outcome of acute pelvic inflammatory disease. J Infect Dis. 1988 Sep;158(3):510–517. doi: 10.1093/infdis/158.3.510. [DOI] [PubMed] [Google Scholar]
- Cates W., Jr, Rolfs R. T., Jr, Aral S. O. Sexually transmitted diseases, pelvic inflammatory disease, and infertility: an epidemiologic update. Epidemiol Rev. 1990;12:199–220. doi: 10.1093/oxfordjournals.epirev.a036054. [DOI] [PubMed] [Google Scholar]
- Cates W., Jr Sexually transmitted organisms and infertility: the proof of the pudding. Sex Transm Dis. 1984 Apr-Jun;11(2):113–116. [PubMed] [Google Scholar]
- Jacobson L., Weström L. Objectivized diagnosis of acute pelvic inflammatory disease. Diagnostic and prognostic value of routine laparoscopy. Am J Obstet Gynecol. 1969 Dec 1;105(7):1088–1098. doi: 10.1016/0002-9378(69)90132-x. [DOI] [PubMed] [Google Scholar]
- Safrin S., Schachter J., Dahrouge D., Sweet R. L. Long-term sequelae of acute pelvic inflammatory disease. A retrospective cohort study. Am J Obstet Gynecol. 1992 Apr;166(4):1300–1305. doi: 10.1016/s0002-9378(11)90626-7. [DOI] [PubMed] [Google Scholar]
- Soper D. E., Brockwell N. J., Dalton H. P. Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. Am J Obstet Gynecol. 1992 Sep;167(3):653–660. doi: 10.1016/s0002-9378(11)91566-x. [DOI] [PubMed] [Google Scholar]
- Svensson L., Mårdh P. A., Weström L. Infertility after acute salpingitis with special reference to Chlamydia trachomatis. Fertil Steril. 1983 Sep;40(3):322–329. doi: 10.1016/s0015-0282(16)47294-8. [DOI] [PubMed] [Google Scholar]
- Weström L. Incidence, prevalence, and trends of acute pelvic inflammatory disease and its consequences in industrialized countries. Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):880–892. doi: 10.1016/0002-9378(80)91077-7. [DOI] [PubMed] [Google Scholar]
- Weström L., Joesoef R., Reynolds G., Hagdu A., Thompson S. E. Pelvic inflammatory disease and fertility. A cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results. Sex Transm Dis. 1992 Jul-Aug;19(4):185–192. [PubMed] [Google Scholar]
- Wølner-Hanssen P., Weström L. Second-look laparoscopy after acute salpingitis. Obstet Gynecol. 1983 Jun;61(6):702–704. [PubMed] [Google Scholar]
