Abstract
Background: Midtrimester genetic amniocentesis is a commonly performed procedure, with acknowledgment of some risk to mother and fetus.
Case: We present an unusual case of midtrimester genetic amniocentesis with bowel injury and resulting septic shock, adult respiratory distress syndrome, and disseminated intravascular coagulation. A total abdominal hysterectomy and bilateral salpingoophorectomy were required for resolution of sepsis. The patient also required prolonged ventilatory support postoperatively.
Conclusion: Although relatively safe, genetic amniocentesis can result in serious morbidity, and attention to technique should be maintained.
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Selected References
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- Hovav Y., Hornstein E., Pollack R. N., Yaffe C. Sepsis due to Clostridium perfringens after second-trimester amniocentesis. Clin Infect Dis. 1995 Jul;21(1):235–236. doi: 10.1093/clinids/21.1.235. [DOI] [PubMed] [Google Scholar]
- Stubblefield P. G., Grimes D. A. Septic abortion. N Engl J Med. 1994 Aug 4;331(5):310–314. doi: 10.1056/NEJM199408043310507. [DOI] [PubMed] [Google Scholar]
- Winkler C. L., Gray S. E., Hauth J. C., Owen J., Tucker J. M. Mid-second-trimester labor induction: concentrated oxytocin compared with prostaglandin E2 vaginal suppositories. Obstet Gynecol. 1991 Feb;77(2):297–300. doi: 10.1097/00006250-199102000-00028. [DOI] [PubMed] [Google Scholar]