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. 1995;2(1):37–42. doi: 10.1155/MBD.1995.37

Synthesis, Characterization and In vitro Antitumour Activity of Novel Organotin Derivatives of 1,2- and 1,7-Dicarba-Closo-dodecaboranes

Marcel Gielen 1,, François Kayser 1,2, Olga B Zhidkova 3, Vladimir Ts Kampel 3, Vladimir l Bregadze 3, Dick de Vos 4, Monique Biesemans 1,2, Bernard Mahieu 5, Rudolph Willem 1,2
PMCID: PMC2364947  PMID: 18472744

Abstract

Several organotin derivatives of 1,2- and 1,7-dicarba-closo-dodecaboranes were synthesized and characterized by 119Sn Mössbauer, 1H, 13C and 119Sn NMR spectroscopy. Their antitumour activities in vitro against cancerous cell lines of human origin are reported.

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