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. 1995;2(4):211–219. doi: 10.1155/MBD.1995.211

Synthesis, Structure and Antitumour Properties of a New 1,2-Propylenediaminetetraacetate-Ruthenium(III) Compound

R Vilaplana 1, M A Romero 2, M Quirós 2, J M Salas 2, F González-Vílchez 1,✉
PMCID: PMC2364974  PMID: 18472768

Abstract

A novel complex formed by ruthenium (III) and the sequestering ligand 1,2-propylenediaminetetraacetic acid (PDTA) has been synthetized and characterized. The structure of the monomeric compound, studied by X-ray diffraction , shows an almost symmetric octahedral geometry around the metal ion, with two chlorine atoms in a cis conformation. The antitumour activity against a variety of murine and human cancers is reported.

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