Synthesis, Characterisation and Biological Activity of Thienoyl- and Furanoyl-Derived Schiff-Base Compounds With 3d Metal Ions

Abstract

Cobalt(ll), copper(ll), nickel(ll) and zinc(ll) metal complexes of 2-carboxybenzylidene thienoylhydrazide HL¹ and 2-carboxybenzylidene furenoylhydrazide HL² of the type [M(L)₂.Cl₂] have been prepared where M = Co(ll) and Ni(ll) and L = HL¹ and HL² (Fig 1) and characterized by their physical, analytical and spectral studies. The different mode of chelation of the ligands with metals and the effect of these metals on their biological properties is discussed.

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