Survival and Histopathological Study of Animals Bearing Ehrlich Tumor Treated With a Rhodium(II) Amidate

Abstract

The survival of 90% of a tumor-bearing population treated with the complex Rh₂ (CF₃CONH)₄ was examined and the pharmacological parameter Surv₉₀ determined. Histopathological alterations raised for this drug in several tissues were studied in Balb-c mice. A Surv₉₀ dose of 3.8x 10^-5 mol/kg was found.

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