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. 2000;7(6):365–370. doi: 10.1155/MBD.2000.365

Development of Novel DNA Cleavage Systems Based on Copper Complexes. Synthesis and Characterisation of Cu(II) Complexes of Hydroxyflavones

F Ben-Allal el Amrani 1, L Perelló 1, J Borrás 1,✉, L Torres 2
PMCID: PMC2365238  PMID: 18475969

Abstract

Copper(II) complexes of several hydroxyflavones were prepared and characterised through their physico-chemical properties. The nuclease activity of three synthesised complexes is reported. These copper(II) complexes present more nuclease activity than the ligands and the copper(II) ion.

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