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. 1993;2(2):99–102. doi: 10.1155/S0962935193000134

Phospholipid derived mediators and glomerulonephritis

E N Wardle 1
PMCID: PMC2365393  PMID: 18475509

Abstract

The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism would seem to be the more efficacious approach for the various disease entities.

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Selected References

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