Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1994 Oct;68(10):6751–6754. doi: 10.1128/jvi.68.10.6751-6754.1994

Genetic identification of a novel hantavirus of the harvest mouse Reithrodontomys megalotis.

B Hjelle 1, F Chavez-Giles 1, N Torrez-Martinez 1, T Yates 1, J Sarisky 1, J Webb 1, M Ascher 1
PMCID: PMC237096  PMID: 8084007

Abstract

We have cloned the S genomic segment of a novel hantavirus of the harvest mouse Reithrodontomys megalotis. The virus is phylogenetically distinct from other hantaviruses. The new hantavirus was identified in harvest mice separated by approximately 1,000 km. A wood rat (Neotoma mexicana) was found to be infected with the harvest mouse hantavirus.

Full text

PDF
6751

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arikawa J., Lapenotiere H. F., Iacono-Connors L., Wang M. L., Schmaljohn C. S. Coding properties of the S and the M genome segments of Sapporo rat virus: comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology. 1990 May;176(1):114–125. doi: 10.1016/0042-6822(90)90236-k. [DOI] [PubMed] [Google Scholar]
  2. Childs J. E., Ksiazek T. G., Spiropoulou C. F., Krebs J. W., Morzunov S., Maupin G. O., Gage K. L., Rollin P. E., Sarisky J., Enscore R. E. Serologic and genetic identification of Peromyscus maniculatus as the primary rodent reservoir for a new hantavirus in the southwestern United States. J Infect Dis. 1994 Jun;169(6):1271–1280. doi: 10.1093/infdis/169.6.1271. [DOI] [PubMed] [Google Scholar]
  3. Chu Y. K., Rossi C., Leduc J. W., Lee H. W., Schmaljohn C. S., Dalrymple J. M. Serological relationships among viruses in the Hantavirus genus, family Bunyaviridae. Virology. 1994 Jan;198(1):196–204. doi: 10.1006/viro.1994.1022. [DOI] [PubMed] [Google Scholar]
  4. Elliott R. M., Schmaljohn C. S., Collett M. S. Bunyaviridae genome structure and gene expression. Curr Top Microbiol Immunol. 1991;169:91–141. doi: 10.1007/978-3-642-76018-1_4. [DOI] [PubMed] [Google Scholar]
  5. Hillis D. M., Huelsenbeck J. P., Cunningham C. W. Application and accuracy of molecular phylogenies. Science. 1994 Apr 29;264(5159):671–677. doi: 10.1126/science.8171318. [DOI] [PubMed] [Google Scholar]
  6. Hjelle B., Jenison S., Torrez-Martinez N., Yamada T., Nolte K., Zumwalt R., MacInnes K., Myers G. A novel hantavirus associated with an outbreak of fatal respiratory disease in the southwestern United States: evolutionary relationships to known hantaviruses. J Virol. 1994 Feb;68(2):592–596. doi: 10.1128/jvi.68.2.592-596.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Jenison S., Yamada T., Morris C., Anderson B., Torrez-Martinez N., Keller N., Hjelle B. Characterization of human antibody responses to four corners hantavirus infections among patients with hantavirus pulmonary syndrome. J Virol. 1994 May;68(5):3000–3006. doi: 10.1128/jvi.68.5.3000-3006.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lee P. W., Amyx H. L., Gajdusek D. C., Yanagihara R. T., Goldgaber D., Gibbs C. J., Jr New hemorrhagic fever with renal syndrome-related virus in rodents in the United States. Lancet. 1982 Dec 18;2(8312):1405–1405. [PubMed] [Google Scholar]
  9. Nerurkar V. R., Song K. J., Gajdusek D. C., Yanagihara R. Genetically distinct hantavirus in deer mice. Lancet. 1993 Oct 23;342(8878):1058–1059. doi: 10.1016/0140-6736(93)92917-i. [DOI] [PubMed] [Google Scholar]
  10. Nichol S. T., Spiropoulou C. F., Morzunov S., Rollin P. E., Ksiazek T. G., Feldmann H., Sanchez A., Childs J., Zaki S., Peters C. J. Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science. 1993 Nov 5;262(5135):914–917. doi: 10.1126/science.8235615. [DOI] [PubMed] [Google Scholar]
  11. Parrington M. A., Kang C. Y. Nucleotide sequence analysis of the S genomic segment of Prospect Hill virus: comparison with the prototype Hantavirus. Virology. 1990 Mar;175(1):167–175. doi: 10.1016/0042-6822(90)90197-y. [DOI] [PubMed] [Google Scholar]
  12. Puthavathana P., Dobbs M., Baek L. J., Chu Y. K., Lee H. W., Kang C. Y. Comparison of nucleotide sequences among hantaviruses belonging to the same serotype: an analysis of amplified DNA by thermal cycle sequencing. Virus Res. 1993 Nov;30(2):161–169. doi: 10.1016/0168-1702(93)90004-7. [DOI] [PubMed] [Google Scholar]
  13. Schmaljohn C. S., Jennings G. B., Hay J., Dalrymple J. M. Coding strategy of the S genome segment of Hantaan virus. Virology. 1986 Dec;155(2):633–643. doi: 10.1016/0042-6822(86)90223-0. [DOI] [PubMed] [Google Scholar]
  14. Spiropoulou C. F., Morzunov S., Feldmann H., Sanchez A., Peters C. J., Nichol S. T. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology. 1994 May 1;200(2):715–723. doi: 10.1006/viro.1994.1235. [DOI] [PubMed] [Google Scholar]
  15. Vapalahti O., Kallio-Kokko H., Salonen E. M., Brummer-Korvenkontio M., Vaheri A. Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein. J Gen Virol. 1992 Apr;73(Pt 4):829–838. doi: 10.1099/0022-1317-73-4-829. [DOI] [PubMed] [Google Scholar]
  16. Xiao S. Y., Leduc J. W., Chu Y. K., Schmaljohn C. S. Phylogenetic analyses of virus isolates in the genus Hantavirus, family Bunyaviridae. Virology. 1994 Jan;198(1):205–217. doi: 10.1006/viro.1994.1023. [DOI] [PubMed] [Google Scholar]
  17. Xiao S. Y., Spik K. W., Li D., Schmaljohn C. S. Nucleotide and deduced amino acid sequences of the M and S genome segments of two Puumala virus isolates from Russia. Virus Res. 1993 Oct;30(1):97–103. doi: 10.1016/0168-1702(93)90019-j. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES