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. 1999 Sep;81(1):141–143. doi: 10.1038/sj.bjc.6690663

A polymorphism in the CYP17 gene is associated with male breast cancer

I E Young 1, K M Kurian 1, C Annink 1,4, I H Kunkler 2, V A Anderson 3, B B Cohen 3, M L Hooper 1, A H Wyllie 1,5, C M Steel 3
PMCID: PMC2374358  PMID: 10487625

Abstract

The CYP17 gene codes for the cytochrome P450c17α enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer. © 1999 Cancer Research Campaign

Keywords: CYP17 polymorphism, male breast cancer

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