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. 1993 Jun;67(6):3671–3673. doi: 10.1128/jvi.67.6.3671-3673.1993

Simian virus 40 small-t antigen binds two zinc ions.

B Turk 1, A Porras 1, M C Mumby 1, K Rundell 1
PMCID: PMC237723  PMID: 8388518

Abstract

Six cysteine residues of the simian virus 40 small-t antigen (small-t) are important for stability of the protein. Stability has been shown to be related to the ability of small-t to bind zinc ions in vitro. Purified small-t expressed either in bacteria or from baculovirus vectors binds two molecules of zinc per molecule of protein. Thus, small-t may resemble GAL4, which contains a Zn(II)2Cys6 binuclear cluster.

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Selected References

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