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. 1993 Oct;39:2157–2162.

Acute otitis media in children. Role of antibiotic therapy.

T Lehnert 1
PMCID: PMC2379855  PMID: 8219863

Abstract

In a review and critical appraisal of the literature on antibiotic therapy for acute otitis media in children between 1939 and 1991, poor evidence supported the routine use of antibiotic therapy. Good evidence supported initial symptomatic treatment and institution of antibiotic therapy only in cases of an irregular course (fever or pain for more than 48 to 72 hours) in children 2 years and older. This approach cannot be recommended for children 2 years and younger because this age group has been excluded from most studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bluestone C. D. Modern management of otitis media. Pediatr Clin North Am. 1989 Dec;36(6):1371–1387. doi: 10.1016/s0031-3955(16)36794-3. [DOI] [PubMed] [Google Scholar]
  2. Bluestone C. D. Otitis media and sinusitis: management and when to refer to the otolaryngologist. Pediatr Infect Dis J. 1987 Jan;6(1):100–106. doi: 10.1097/00006454-198701000-00049. [DOI] [PubMed] [Google Scholar]
  3. Bluestone C. D. Otitis media in children: to treat or not to treat? N Engl J Med. 1982 Jun 10;306(23):1399–1404. doi: 10.1056/NEJM198206103062305. [DOI] [PubMed] [Google Scholar]
  4. Bollag U., Bollag-Albrecht E. Recommendations derived from practice audit for the treatment of acute otitis media. Lancet. 1991 Jul 13;338(8759):96–99. doi: 10.1016/0140-6736(91)90086-5. [DOI] [PubMed] [Google Scholar]
  5. Burke P., Bain J., Robinson D., Dunleavey J. Acute red ear in children: controlled trial of non-antibiotic treatment in general practice. BMJ. 1991 Sep 7;303(6802):558–562. doi: 10.1136/bmj.303.6802.558. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. De Melker R. A., Burke P. D. Epidemiology of otitis media and the role of the general practitioner in management. Fam Pract. 1988 Dec;5(4):307–313. doi: 10.1093/fampra/5.4.307. [DOI] [PubMed] [Google Scholar]
  7. Dixon T. International approaches to otitis media. Can Fam Physician. 1990 Sep;36:1451–1455. [PMC free article] [PubMed] [Google Scholar]
  8. Froom J., Culpepper L., Grob P., Bartelds A., Bowers P., Bridges-Webb C., Grava-Gubins I., Green L., Lion J., Somaini B. Diagnosis and antibiotic treatment of acute otitis media: report from International Primary Care Network. BMJ. 1990 Mar 3;300(6724):582–586. doi: 10.1136/bmj.300.6724.582. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Giebink G. S., Canafax D. M. Controversies in the management of acute otitis media. Adv Pediatr Infect Dis. 1988;3:47–63. [PubMed] [Google Scholar]
  10. Halsted C., Lepow M. L., Balassanian N., Emmerich J., Wolinsky E. Otitis media. Clinical observations, microbiology, and evaluation of therapy. Am J Dis Child. 1968 May;115(5):542–551. doi: 10.1001/archpedi.1968.02100010544003. [DOI] [PubMed] [Google Scholar]
  11. Howie V. M., Ploussard J. H. Efficacy of fixed combination antibiotics versus separate components in otitis media. Effectiveness of erythromycin estrolate, triple sulfonamide, ampicillin, erythromycin estolate- triple sulfonamide, and placebo in 280 patients with acute otitis media under two and one-half years of age. Clin Pediatr (Phila) 1972 Apr;11(4):205–214. doi: 10.1177/000992287201100407. [DOI] [PubMed] [Google Scholar]
  12. Laxdal O. E., Merida J., Jones R. H. Treatment of acute otitis media: a controlled study of 142 children. Can Med Assoc J. 1970 Feb 14;102(3):263–268. [PMC free article] [PubMed] [Google Scholar]
  13. Mygind N., Meistrup-Larsen K. I., Thomsen J., Thomsen V. F., Josefsson K., Sørensen H. Penicillin in acute otitis media: a double-blind placebo-controlled trial. Clin Otolaryngol Allied Sci. 1981 Feb;6(1):5–13. doi: 10.1111/j.1365-2273.1981.tb01781.x. [DOI] [PubMed] [Google Scholar]
  14. Paradise J. L. Otitis media in infants and children. Pediatrics. 1980 May;65(5):917–943. [PubMed] [Google Scholar]
  15. Stool S. Otitis media. Update on a common, frustrating problem. Postgrad Med. 1989 Jan;85(1):40-7, 51, 53. doi: 10.1080/00325481.1989.11700532. [DOI] [PubMed] [Google Scholar]
  16. TOWNSEND E. H., Jr OTITIS MEDIA IN PEDIATRIC PRACTICE. N Y State J Med. 1964 Jun 15;64:1591–1597. [PubMed] [Google Scholar]
  17. van Buchem F. L., Dunk J. H., van't Hof M. A. Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children. Lancet. 1981 Oct 24;2(8252):883–887. doi: 10.1016/s0140-6736(81)91388-x. [DOI] [PubMed] [Google Scholar]
  18. van Buchem F. L., Peeters M. F., van 't Hof M. A. Acute otitis media: a new treatment strategy. Br Med J (Clin Res Ed) 1985 Apr 6;290(6474):1033–1037. doi: 10.1136/bmj.290.6474.1033. [DOI] [PMC free article] [PubMed] [Google Scholar]

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