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. 1993 Dec;67(12):7246–7253. doi: 10.1128/jvi.67.12.7246-7253.1993

Vesicular stomatitis virus M protein may be inside the ribonucleocapsid coil.

A Barge 1, Y Gaudin 1, P Coulon 1, R W Ruigrok 1
PMCID: PMC238187  PMID: 8230447

Abstract

Vesicular stomatitis virus is an enveloped virus with an external glycoprotein G and a nucleocapsid that form, together with the M protein, a tight helically coiled structure: the skeleton. Negative staining and immunoelectron microscopy studies on skeleton preparations were performed to determine the localization of the M protein. These studies have resulted in a new model for the structure of rhabdoviruses in which the nucleocapsid is wound around a core containing the M protein. This model predicts contact between M and lipid only at the extreme ends of the skeleton, which is confirmed by skeleton-liposome binding studies.

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Selected References

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