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. 1985 Apr;49(4):904–907. doi: 10.1128/aem.49.4.904-907.1985

Mechanism of action of aflatoxin B1 in Bacillus megaterium.

R P Tiwari, C K Dham, T C Bhalla, S S Saini, D V Vadehra
PMCID: PMC238467  PMID: 3923926

Abstract

Bacillus megaterium cells from various growth phases were equally susceptible to the lethal effects of aflatoxin B1. Known surfactants (EDTA and Tween-80) accentuated the effects of aflatoxin B1. Viability and inulin uptake in aflatoxin B1-exposed cells decreased considerably. The effect was concentration dependent. A straight-line relationship observed in the death curve indicated a single target for aflatoxin B1 action in B. megaterium. Leakage of intracellular constituents in B. megaterium was also concentration dependent, and this can be related to the extent of cell membrane damage.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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