Abstract
In many countries, measles surveillance relies heavily on the use of a standard clinical case definition; however, the clinical signs and symptoms of measles are similar to those of dengue. For example, during 1985, in Puerto Rico, 22 (23%) of 94 cases of illnesses with rashes that met the measles clinical case definition were serologically confirmed as measles, but 32 (34%) others were serologically confirmed as dengue. Retrospective analysis at the San Juan Laboratories of the Centers for Disease Control showed also that at least 28% of all laboratory-confirmed cases of dengue in Puerto Rico in 1985 met the measles clinical case definition. If the true measles vaccine efficacy (VE) is assumed to be 90%, the occurrence of laboratory-confirmed dengue cases that meet the measles clinical case definition results in a reduction of the apparent measles VE to only 64% (a 29% relative reduction from the true VE). The results of the study demonstrate the importance of a laboratory-based surveillance system in measles control or elimination efforts in dengue-endemic areas.
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Selected References
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- CLARKE D. H., CASALS J. Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg. 1958 Sep;7(5):561–573. doi: 10.4269/ajtmh.1958.7.561. [DOI] [PubMed] [Google Scholar]
- Centers for Disease Control (CDC) Classification of measles cases and categorization of measles elimination programs. MMWR Morb Mortal Wkly Rep. 1983 Jan 7;31(52):707–711. [PubMed] [Google Scholar]
- Gubler D. J., Kuno G., Sather G. E., Velez M., Oliver A. Mosquito cell cultures and specific monoclonal antibodies in surveillance for dengue viruses. Am J Trop Med Hyg. 1984 Jan;33(1):158–165. doi: 10.4269/ajtmh.1984.33.158. [DOI] [PubMed] [Google Scholar]
- Henderson R. H., Keja J., Hayden G., Galazka A., Clements J., Chan C. Immunizing the children of the world: progress and prospects. Bull World Health Organ. 1988;66(5):535–543. [PMC free article] [PubMed] [Google Scholar]
- Morens D. M., Rigau-Pérez J. G., López-Correa R. H., Moore C. G., Ruiz-Tibén E. E., Sather G. E., Chiriboga J., Eliason D. A., Casta-Velez A., Woodall J. P. Dengue in Puerto Rico, 1977: public health response to characterize and control an epidemic of multiple serotypes. Am J Trop Med Hyg. 1986 Jan;35(1):197–211. doi: 10.4269/ajtmh.1986.35.197. [DOI] [PubMed] [Google Scholar]
- Orenstein W. A., Bernier R. H., Dondero T. J., Hinman A. R., Marks J. S., Bart K. J., Sirotkin B. Field evaluation of vaccine efficacy. Bull World Health Organ. 1985;63(6):1055–1068. [PMC free article] [PubMed] [Google Scholar]