Skip to main content
PMC home page
Sarcoma logoLink to Sarcoma
. 2002 Mar;6(1):47–50. doi: 10.1080/13577140220127558

Leiomyosarcoma of Bone Arising in Association with a Bone Infarct

M Petra 1, C L M H Gibbons 1, N A Athanasou 1,✉
PMCID: PMC2395491  PMID: 18521345

Abstract

Both primary leiomyosarcoma of bone and sarcoma arising in association with a bone infarct are rare events. In this case report we describe for the first time a case of leiomyosarcoma arising in a bone infarct. The tumour arose in a medullary infarct in the proximal femur of an elderly patient. As in other cases of sarcoma arising in a bone infarct, the prognosis was poor, the patient dying within 6 months of diagnosis.

Full Text

The Full Text of this article is available as a PDF (477.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abdelwahab I. F., Hermann G., Kenan S., Klein M. J., Lewis M. M. Case report 794. Primary leiomyosarcoma of the right femur (fig. 4). Skeletal Radiol. 1993;22(5):379–381. doi: 10.1007/BF00198401. [DOI] [PubMed] [Google Scholar]
  2. Abdelwahab I. F., Klein M. J., Hermann G., Springfield D. Angiosarcomas associated with bone infarcts. Skeletal Radiol. 1998 Oct;27(10):546–551. doi: 10.1007/s002560050435. [DOI] [PubMed] [Google Scholar]
  3. Aoki T., Ozeki Y., Watanabe M., Tanaka S., Isaki H., Terahata S. Development of primary leiomyosarcoma of the sternum postirradiation: report of a case. Surg Today. 1998;28(12):1326–1328. doi: 10.1007/BF02482828. [DOI] [PubMed] [Google Scholar]
  4. BULLOUGH P. G., KAMBOLIS C. P., MARCOVE R. C., JAFFE H. L. BONE INFARCTIONS NOT ASSOCIATED WITH CAISSON DISEASE. J Bone Joint Surg Am. 1965 Apr;47:477–491. [PubMed] [Google Scholar]
  5. Berlin O., Angervall L., Kindblom L. G., Berlin I. C., Stener B. Primary leiomyosarcoma of bone. A clinical, radiographic, pathologic-anatomic, and prognostic study of 16 cases. Skeletal Radiol. 1987;16(5):364–376. doi: 10.1007/BF00350962. [DOI] [PubMed] [Google Scholar]
  6. Desai P., Perino G., Present D., Steiner G. C. Sarcoma in association with bone infarcts. Report of five cases. Arch Pathol Lab Med. 1996 May;120(5):482–489. [PubMed] [Google Scholar]
  7. Eady J. L., McKinney J. D., McDonald E. C. Primary leiomyosarcoma of bone. A case report and review of the literature. J Bone Joint Surg Am. 1987 Feb;69(2):287–289. [PubMed] [Google Scholar]
  8. Evans D. M., Sanerkin N. G. Primary leiomyosarcoma of bone. J Pathol Bacteriol. 1965 Jul;90(1):348–350. doi: 10.1002/path.1700900145. [DOI] [PubMed] [Google Scholar]
  9. FUREY J. G., FERRER-TORRER-TORELLS M., REAGAN J. W. Fibrosarcoma arising at the site of bone infarcts. A report of 2 cases. J Bone Joint Surg Am. 1960 Jul;42-A:802–810. [PubMed] [Google Scholar]
  10. Jundt G., Moll C., Nidecker A., Schilt R., Remagen W. Primary leiomyosarcoma of bone: report of eight cases. Hum Pathol. 1994 Nov;25(11):1205–1212. doi: 10.1016/0046-8177(94)90038-8. [DOI] [PubMed] [Google Scholar]
  11. Khoddami M., Bedard Y. C., Bell R. S., Kandel R. A. Primary leiomyosarcoma of bone: report of seven cases and review of the literature. Arch Pathol Lab Med. 1996 Jul;120(7):671–675. [PubMed] [Google Scholar]
  12. Mirra J. M., Bullough P. G., Marcove R. C., Jacobs B., Huvos A. G. Malignant fibrous histiocytoma and osteosarcoma in association with bone infarcts; report of four cases, two in caisson workers. J Bone Joint Surg Am. 1974 Jul;56(5):932–940. [PubMed] [Google Scholar]
  13. Myers J. L., Arocho J., Bernreuter W., Dunham W., Mazur M. T. Leiomyosarcoma of bone. A clinicopathologic, immunohistochemical, and ultrastructural study of five cases. Cancer. 1991 Feb 15;67(4):1051–1056. doi: 10.1002/1097-0142(19910215)67:4<1051::aid-cncr2820670431>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  14. Overgaard J., Frederiksen P., Helmig O., Jensen O. M. Primary leiomyosarcoma of bone. Cancer. 1977 Apr;39(4):1664–1671. doi: 10.1002/1097-0142(197704)39:4<1664::aid-cncr2820390441>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  15. Pins M. R., Mankin H. J., Xavier R. J., Rosenthal D. I., Dickersin G. R., Rosenberg A. E. Malignant epithelioid hemangioendothelioma of the tibia associated with a bone infarct in a patient who had Gaucher disease. A case report. J Bone Joint Surg Am. 1995 May;77(5):777–781. doi: 10.2106/00004623-199505000-00015. [DOI] [PubMed] [Google Scholar]
  16. Shamsuddin A. K., Reyes F., Harvey J. W., Toker C. Primary leiomyosarcoma of bone. Hum Pathol. 1980 Sep;11(5 Suppl):581–583. [PubMed] [Google Scholar]
  17. Torres F. X., Kyriakos M. Bone infarct-associated osteosarcoma. Cancer. 1992 Nov 15;70(10):2418–2430. doi: 10.1002/1097-0142(19921115)70:10<2418::aid-cncr2820701007>3.0.co;2-e. [DOI] [PubMed] [Google Scholar]
  18. Wang T. Y., Erlandson R. A., Marcove R. C., Huvos A. G. Primary leiomyosarcoma of bone. Arch Pathol Lab Med. 1980 Feb;104(2):100–104. [PubMed] [Google Scholar]
  19. Wirbel R. J., Verelst S., Hanselmann R., Remberger K., Kubale R., Mutschler W. E. Primary leiomyosarcoma of bone: clinicopathologic, immunohistochemical, and molecular biologic aspects. Ann Surg Oncol. 1998 Oct-Nov;5(7):635–641. doi: 10.1007/BF02303834. [DOI] [PubMed] [Google Scholar]
  20. Young M. P., Freemont A. J. Primary leiomyosarcoma of bone. Histopathology. 1991 Sep;19(3):257–262. doi: 10.1111/j.1365-2559.1991.tb00031.x. [DOI] [PubMed] [Google Scholar]

Articles from Sarcoma are provided here courtesy of Wiley

RESOURCES