Figure 5.

Amino acid sequence comparison of the BC domains of T. gondii ACC1 and ACC2 with other ACCs, including those of apicomplexa. Sequence alignment and the phylogenetic tree (Neighbor-Joining Method, distances corrected for multiple substitutions) were created by using clustal x (19), with the Anabaena 7120 BC domain sequence as an outgroup. The length of the alignment is 550 amino acids, but shorter sequences from C. parvum, P. falciparum, and P. knowlesi ACCs were deduced from partial genomic sequences. Numbers at the nodes indicate bootstrap values (%). The sequences reported in this paper are underlined, and all are available from GenBank.