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. 1979;57(Suppl):33–36.

Recent developments in production and purification of malaria antigens: In vitro propagation of Plasmodium falciparum for merozoite antigens*

R G Brackett, G C Cole, T J Green, R L Jacobs
PMCID: PMC2395713  PMID: 397007

Abstract

A system with continuous flow of medium that uses disposable tissue culture flasks for the in vitro cultivation of P. falciparum is described. This scaled-up modification of the Trager and Jensen method gives merozoite yields sufficient for experimental vaccine studies in animals. A method of increasing the yield of merozoites by decreasing the pH of the medium is presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Rowe A. W., Eyster E., Kellner A. Liquid nitrogen preservation of red blood cells for transfusion; a low glycerol-rapid freeze procedure. Cryobiology. 1968 Sep-Oct;5(2):119–128. doi: 10.1016/s0011-2240(68)80154-3. [DOI] [PubMed] [Google Scholar]
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