Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1981;59(1):1–8.

The immunology of filariasis*

Scientific Working Group on Filariasis
PMCID: PMC2396020  PMID: 7020971

Abstract

This report summarizes the available information on the immunology of filariasis, and discusses immunodiagnosis and the immunological factors influencing the host—parasite relationship in lymphatic filariasis and onchocerciasis. Several areas that require further research are identified, particularly concerning the development of new serological techniques, and the fractionation of specific antigens. The problems associated with vaccine development are considered and the importance of finding better animal models for research is stressed.

Full text

PDF
1

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Haque A., Lefebvre M. N., Ogilvie B. M., Capron A. Dipetalonema viteae in hamsters: effect of antiserum or immunization with parasite extracts on production of microfilariae. Parasitology. 1978 Feb;76(1):61–75. doi: 10.1017/s0031182000047399. [DOI] [PubMed] [Google Scholar]
  2. Mackenzie C. D., Preston P. M., Ogilvie B. M. Immunological properties of the surface of parasitic nematodes. Nature. 1978 Dec 21;276(5690):826–828. doi: 10.1038/276826a0. [DOI] [PubMed] [Google Scholar]
  3. Miller T. A. Vaccination against the canine hookworm diseases. Adv Parasitol. 1971;9:153–183. doi: 10.1016/s0065-308x(08)60161-x. [DOI] [PubMed] [Google Scholar]
  4. Weeke B., Lowenstein H. Allergens identified in crossed radioimmunoelectrophoresis. Scand J Immunol Suppl. 1973;1:149–153. doi: 10.1111/j.1365-3083.1973.tb03796.x. [DOI] [PubMed] [Google Scholar]
  5. de Savigny D. H., Voller A., Woodruff A. W. Toxocariasis: serological diagnosis by enzyme immunoassay. J Clin Pathol. 1979 Mar;32(3):284–288. doi: 10.1136/jcp.32.3.284. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES