Skip to main content
NCBI home page
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1994 Jan;70(819):41–43. doi: 10.1136/pgmj.70.819.41

Pulmonary hypertension associated with non-cirrhotic portal hypertension in systemic lupus erythematosus.

D Woolf 1, M D Voigt 1, K Jaskiewicz 1, A A Kalla 1
PMCID: PMC2397573  PMID: 8140019

Abstract

A case of non-cirrhotic portal hypertension in a patient with systemic lupus erythematosus, the first of our knowledge, is described. Severe pulmonary hypertension was associated with the portal hypertension and with markers of active auto-immunity. Pulmonary hypertension has not previously been associated with non-cirrhotic portal hypertension. The coexistence of vasculopathy of the portal and pulmonary vascular beds in this patient with active autoimmunity supports the postulate that portal-pulmonary hypertension may be immunologically mediated.

Full text

PDF
41

Images in this article

42Figure 1
on p.42

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asherson R. A., Mackworth-Young C. G., Boey M. L., Hull R. G., Saunders A., Gharavi A. E., Hughes G. R. Pulmonary hypertension in systemic lupus erythematosus. Br Med J (Clin Res Ed) 1983 Oct 8;287(6398):1024–1025. doi: 10.1136/bmj.287.6398.1024-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fukuda K., Kage M., Arakawa M., Nakashima T. Portal vein or hepatic vein? A curious aberrant vasculature in the liver with idiopathic portal hypertension. Acta Pathol Jpn. 1985 Jul;35(4):885–897. [PubMed] [Google Scholar]
  3. Hadengue A., Benhayoun M. K., Lebrec D., Benhamou J. P. Pulmonary hypertension complicating portal hypertension: prevalence and relation to splanchnic hemodynamics. Gastroenterology. 1991 Feb;100(2):520–528. doi: 10.1016/0016-5085(91)90225-a. [DOI] [PubMed] [Google Scholar]
  4. KERBEL N. C. Pulmonary hypertension and portal hypertension. Can Med Assoc J. 1962 Nov 10;87:1022–1026. [PMC free article] [PubMed] [Google Scholar]
  5. Kuramochi S., Tashiro Y., Torikata C., Watanabe Y. Systemic lupus erythematosus associated with multiple nodular hyperplasia of the liver. Acta Pathol Jpn. 1982 May;32(3):547–560. doi: 10.1111/j.1440-1827.1982.tb01410.x. [DOI] [PubMed] [Google Scholar]
  6. Morrison E. B., Gaffney F. A., Eigenbrodt E. H., Reynolds R. C., Buja L. M. Severe pulmonary hypertension associated with macronodular (postnecrotic) cirrhosis and autoimmune phenomena. Am J Med. 1980 Oct;69(4):513–519. doi: 10.1016/0002-9343(80)90461-1. [DOI] [PubMed] [Google Scholar]
  7. Runyon B. A., LaBrecque D. R., Anuras S. The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature. Am J Med. 1980 Aug;69(2):187–194. doi: 10.1016/0002-9343(80)90378-2. [DOI] [PubMed] [Google Scholar]
  8. Sama S. K., Bhargava S., Nath N. G., Talwar J. R., Nayak N. C., Tandon B. N., Wig K. L. Noncirrhotic portal fibrosis. Am J Med. 1971 Aug;51(2):160–169. doi: 10.1016/0002-9343(71)90234-8. [DOI] [PubMed] [Google Scholar]
  9. Squara P., Dahan M., Juliard J. M., Ramond M. J., Fabiani B., Gourgon R. Hypertension artérielle pulmonaire révélant une cirrhose hépatique. Ann Med Interne (Paris) 1987;138(5):377–378. [PubMed] [Google Scholar]
  10. Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES