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. 1994 Jun;70(824):433–435. doi: 10.1136/pgmj.70.824.433

Do carotid bruits predict disease of the internal carotid arteries?

K N Davies 1, P R Humphrey 1
PMCID: PMC2397706  PMID: 8029163

Abstract

A carotid bruit is often thought of as a reliable sign of extracranial carotid artery disease. In addition finding a bruit may precipitate a referral to hospital. Carotid endarterectomy has now been shown to be beneficial in patients with symptomatic carotid territory ischaemia and 70-99% stenosis of the relevant carotid artery, therefore it is important that such patients are detected and referred. In this study of 331 consecutive patients referred to a specialist cerebrovascular clinic we examined the practical value of a carotid bruit mentioned by the referring practitioner. All patients underwent clinical assessment, evaluation of risk factors and Doppler duplex scanning of the carotid arteries. A bruit was stated in the referral letter of 110 (33%) patients. Moderate (30-69%) or severe (70-99%) stenosis was present in 37% of patients with, and 17% of those without a carotid bruit (P < 0.001). We found a carotid bruit was a poor predictor of such disease (positive predictive value, 37%). The false negative rate for severe disease was 43%. Normal carotid arteries were found in 32% of patients with a bruit. We therefore suggest that all patients with suspected carotid territory ischaemia should be referred for assessment whether there is a bruit present or not.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnes R. W. Noninvasive evaluation of the carotid bruit. Annu Rev Med. 1980;31:201–218. doi: 10.1146/annurev.me.31.020180.001221. [DOI] [PubMed] [Google Scholar]
  2. FISHER C. M. Cranial bruit associated with occlusion of the internal carotid artery. Neurology. 1957 May;7(5):299–306. doi: 10.1212/wnl.7.5.299. [DOI] [PubMed] [Google Scholar]
  3. Hankey G. J., Warlow C. P. Symptomatic carotid ischaemic events: safest and most cost effective way of selecting patients for angiography, before carotid endarterectomy. BMJ. 1990 Jun 9;300(6738):1485–1491. doi: 10.1136/bmj.300.6738.1485. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Harrison M. J., Marshall J. Indications for angiography and surgery in carotid artery disease. Br Med J. 1975 Mar 15;1(5958):616–618. doi: 10.1136/bmj.1.5958.616. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hennerici M., Aulich A., Sandmann W., Freund H. J. Incidence of asymptomatic extracranial arterial disease. Stroke. 1981 Nov-Dec;12(6):750–758. doi: 10.1161/01.str.12.6.750. [DOI] [PubMed] [Google Scholar]
  6. Humphrey P., Sandercock P., Slattery J. A simple method to improve the accuracy of non-invasive ultrasound in selecting TIA patients for cerebral angiography. J Neurol Neurosurg Psychiatry. 1990 Nov;53(11):966–971. doi: 10.1136/jnnp.53.11.966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Ingall T. J., Homer D., Whisnant J. P., Baker H. L., Jr, O'Fallon W. M. Predictive value of carotid bruit for carotid atherosclerosis. Arch Neurol. 1989 Apr;46(4):418–422. doi: 10.1001/archneur.1989.00520400078023. [DOI] [PubMed] [Google Scholar]
  8. Lusiani L., Visona' A., Castellani V., Ronsisvalle G., Bonanome A., Pagnan A. Prevalence of atherosclerotic lesions at the carotid bifurcation in patients with asymptomatic bruits: an echo-Doppler (duplex) study. Angiology. 1985 Apr;36(4):235–239. doi: 10.1177/000331978503600406. [DOI] [PubMed] [Google Scholar]
  9. North American Symptomatic Carotid Endarterectomy Trial Collaborators Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991 Aug 15;325(7):445–453. doi: 10.1056/NEJM199108153250701. [DOI] [PubMed] [Google Scholar]
  10. Pessin M. S., Panis W., Prager R. J., Millan V. G., Scott R. M. Auscultation of cervical and ocular bruits in extracranial carotid occlusive disease: a clinical and angiographic study. Stroke. 1983 Mar-Apr;14(2):246–249. doi: 10.1161/01.str.14.2.246. [DOI] [PubMed] [Google Scholar]
  11. Sandok B. A., Whisnant J. P., Furlan A. J., Mickell J. L. Carotid artery bruits: prevalence survey and differential diagnosis. Mayo Clin Proc. 1982 Apr;57(4):227–230. [PubMed] [Google Scholar]
  12. Wilson L. A., Russell R. W. Amaurosis fugax and carotid artery disease: indications for angiography. Br Med J. 1977 Aug 13;2(6084):435–437. doi: 10.1136/bmj.2.6084.435. [DOI] [PMC free article] [PubMed] [Google Scholar]

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