Abstract
We report a 71 year old lady who presented with weight loss, rectal bleeding and bilateral foot drop having been previously fit and well. Clinical examination, laboratory investigation and postmortem examination confirmed the diagnosis of active Crohn's disease and acute peripheral neuropathy. The clinical course of this patient suggests that the peripheral neuropathy might have resulted from the common pathogenesis for Crohn's disease.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cohen M. G., Webb J. Brachial neuritis with colitic arthritis. Ann Intern Med. 1987 May;106(5):780–781. doi: 10.7326/0003-4819-106-5-780_2. [DOI] [PubMed] [Google Scholar]
- Contamin F., Ollat H., Lévy V. G., Thierman-Duffaud D. Atteinte des systèmes nerveux périphérique et pyramidal au cours d'une maladie de Crohn. Rôle déterminant d'une carence folique. Sem Hop. 1983 May 5;59(18):1381–1385. [PubMed] [Google Scholar]
- Danzi J. T. Extraintestinal manifestations of idiopathic inflammatory bowel disease. Arch Intern Med. 1988 Feb;148(2):297–302. [PubMed] [Google Scholar]
- Duffy L. F., Daum F., Fisher S. E., Selman J., Vishnubhakat S. M., Aiges H. W., Markowitz J. F., Silverberg M. Peripheral neuropathy in Crohn's disease patients treated with metronidazole. Gastroenterology. 1985 Mar;88(3):681–684. doi: 10.1016/0016-5085(85)90137-4. [DOI] [PubMed] [Google Scholar]
- Humbert P., Monnier G., Billerey C., Birgen C., Dupond J. L. Polyneuropathy: an unusual extraintestinal manifestation of Crohn's disease. Acta Neurol Scand. 1989 Oct;80(4):301–306. doi: 10.1111/j.1600-0404.1989.tb03883.x. [DOI] [PubMed] [Google Scholar]
- Nemni R., Fazio R., Corbo M., Sessa M., Comi G., Canal N. Peripheral neuropathy associated with Crohn's disease. Neurology. 1987 Aug;37(8):1414–1417. doi: 10.1212/wnl.37.8.1414. [DOI] [PubMed] [Google Scholar]
- Rankin G. B., Watts H. D., Melnyk C. S., Kelley M. L., Jr National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications. Gastroenterology. 1979 Oct;77(4 Pt 2):914–920. [PubMed] [Google Scholar]