Skip to main content
NCBI home page
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1995 Mar;71(833):151–152. doi: 10.1136/pgmj.71.833.151

Early diagnosis of Parkinson's disease.

A M Bakheit 1
PMCID: PMC2398181  PMID: 7746773

Abstract

Early diagnosis of Parkinson's disease is often difficult. The insidious onset of the disease, its slow progression and the lack of laboratory tests to confirm the diagnosis contribute to this difficulty. Nevertheless, early diagnosis can be greatly facilitated by the systematic application of diagnostic clinical criteria and the selective use of radiological and laboratory tests.

Full text

PDF
151

Images in this article

152Figure
on p.152

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bonuccelli U., Piccini P., Del Dotto P., Rossi G., Corsini G. U., Muratorio A. Apomorphine test for dopaminergic responsiveness: a dose assessment study. Mov Disord. 1993 Apr;8(2):158–164. doi: 10.1002/mds.870080207. [DOI] [PubMed] [Google Scholar]
  2. Clough C. G. A case of normal pressure hydrocephalus presenting as levodopa responsive parkinsonism. J Neurol Neurosurg Psychiatry. 1987 Feb;50(2):234–234. doi: 10.1136/jnnp.50.2.234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. D'Costa D. F., Abbott R. J., Pye I. F., Millac P. A. The apomorphine test in parkinsonian syndromes. J Neurol Neurosurg Psychiatry. 1991 Oct;54(10):870–872. doi: 10.1136/jnnp.54.10.870. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Diamond S. G., Markham C. H., Hoehn M. M., McDowell F. H., Muenter M. D. Effect of age at onset on progression and mortality in Parkinson's disease. Neurology. 1989 Sep;39(9):1187–1190. doi: 10.1212/wnl.39.9.1187. [DOI] [PubMed] [Google Scholar]
  5. Gibb W. R., Lees A. J. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):745–752. doi: 10.1136/jnnp.51.6.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hughes A. J., Ben-Shlomo Y., Daniel S. E., Lees A. J. What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study. Neurology. 1992 Jun;42(6):1142–1146. doi: 10.1212/wnl.42.6.1142. [DOI] [PubMed] [Google Scholar]
  7. Hughes A. J., Lees A. J., Stern G. M. Apomorphine test to predict dopaminergic responsiveness in parkinsonian syndromes. Lancet. 1990 Jul 7;336(8706):32–34. doi: 10.1016/0140-6736(90)91531-e. [DOI] [PubMed] [Google Scholar]
  8. Markham C. H., Diamond S. G. Evidence to support early levodopa therapy in Parkinson disease. Neurology. 1981 Feb;31(2):125–131. doi: 10.1212/wnl.31.2.125. [DOI] [PubMed] [Google Scholar]
  9. Mutch W. J., Dingwall-Fordyce I., Downie A. W., Paterson J. G., Roy S. K. Parkinson's disease in a Scottish city. Br Med J (Clin Res Ed) 1986 Feb 22;292(6519):534–536. doi: 10.1136/bmj.292.6519.534. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nausieda P. A., Weiner W. J., Klawans H. L. Dystonic foot response of Parkinsonism. Arch Neurol. 1980 Mar;37(3):132–136. doi: 10.1001/archneur.1980.00500520030003. [DOI] [PubMed] [Google Scholar]
  11. Newman R. P., LeWitt P. A., Jaffe M., Calne D. B., Larsen T. A. Motor function in the normal aging population: treatment with levodopa. Neurology. 1985 Apr;35(4):571–573. doi: 10.1212/wnl.35.4.571. [DOI] [PubMed] [Google Scholar]
  12. Singer C., Weiner W. J., Sanchez-Ramos J. R. Autonomic dysfunction in men with Parkinson's disease. Eur Neurol. 1992;32(3):134–140. doi: 10.1159/000116810. [DOI] [PubMed] [Google Scholar]
  13. Stern M. B., Braffman B. H., Skolnick B. E., Hurtig H. I., Grossman R. I. Magnetic resonance imaging in Parkinson's disease and parkinsonian syndromes. Neurology. 1989 Nov;39(11):1524–1526. doi: 10.1212/wnl.39.11.1524. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES