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. 1991 Feb;65(2):985–988. doi: 10.1128/jvi.65.2.985-988.1991

Sindbis virus nsP1 functions in negative-strand RNA synthesis.

Y F Wang 1, S G Sawicki 1, D L Sawicki 1
PMCID: PMC239844  PMID: 1824787

Abstract

A mutation at nucleotide 1101 of Sindbis virus ts11 nsP1 caused temperature-sensitive negative-strand synthesis and suppressed the 24R phenotype, which is caused by a mutation in nsP4. Nonstructural proteins synthesized and accumulated by ts11 at 40 degrees C did not cause the reactivation of negative-strand synthesis upon return to 30 degrees C and did not prevent the formation of new replication complexes at 30 degrees C.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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