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. 1991 Aug;67(790):742–744. doi: 10.1136/pgmj.67.790.742

Medical disorders in Alzheimer's disease and vascular dementia.

H Förstl 1, N Cairns 1, A Burns 1, P Luthert 1
PMCID: PMC2399039  PMID: 1754524

Abstract

The clinical and postmortem findings of 29 patients with Alzheimer's disease were evaluated and compared to the findings of 19 patients with vascular dementia. The patients with Alzheimer's disease had received treatment for an average of 2.0 internal medical disorders, the patients with vascular dementia for 2.1 disorders. The average number of medical diseases found at postmortem was 3.7 in the group with Alzheimer's dementia and 4.1 in vascular dementia. Apart from a marginally increased rate of peripheral occlusive artery disease in vascular dementia, the proportions of the most common disorders of the cardiovascular, genitourinary, gastrointestinal and endocrinological disorders and the most common causes of death did not differ significantly between these groups. Therefore patients with Alzheimer's disease should receive the same internal medical attention as patients with vascular dementia.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burns A., Luthert P., Levy R., Jacoby R., Lantos P. Accuracy of clinical diagnosis of Alzheimer's disease. BMJ. 1990 Nov 3;301(6759):1026–1026. doi: 10.1136/bmj.301.6759.1026. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Erkinjuntti T. Differential diagnosis between Alzheimer's disease and vascular dementia: evaluation of common clinical methods. Acta Neurol Scand. 1987 Dec;76(6):433–442. doi: 10.1111/j.1600-0404.1987.tb03599.x. [DOI] [PubMed] [Google Scholar]
  3. Henderson A. S. The risk factors for Alzheimer's disease: a review and a hypothesis. Acta Psychiatr Scand. 1988 Sep;78(3):257–275. doi: 10.1111/j.1600-0447.1988.tb06336.x. [DOI] [PubMed] [Google Scholar]
  4. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984 Jul;34(7):939–944. doi: 10.1212/wnl.34.7.939. [DOI] [PubMed] [Google Scholar]
  5. Mölsä P. K., Marttila R. J., Rinne U. K. Survival and cause of death in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand. 1986 Aug;74(2):103–107. doi: 10.1111/j.1600-0404.1986.tb04634.x. [DOI] [PubMed] [Google Scholar]
  6. Sulkava R., Haltia M., Paetau A., Wikström J., Palo J. Accuracy of clinical diagnosis in primary degenerative dementia: correlation with neuropathological findings. J Neurol Neurosurg Psychiatry. 1983 Jan;46(1):9–13. doi: 10.1136/jnnp.46.1.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Thal L. J., Grundman M., Klauber M. R. Dementia: characteristics of a referral population and factors associated with progression. Neurology. 1988 Jul;38(7):1083–1090. doi: 10.1212/wnl.38.7.1083. [DOI] [PubMed] [Google Scholar]
  8. Tresch D. D., Folstein M. F., Rabins P. V., Hazzard W. R. Prevalence and significance of cardiovascular disease and hypertension in elderly patients with dementia and depression. J Am Geriatr Soc. 1985 Aug;33(8):530–537. doi: 10.1111/j.1532-5415.1985.tb04616.x. [DOI] [PubMed] [Google Scholar]
  9. Wolf-Klein G. P., Siverstone F. A., Brod M. S., Levy A., Foley C. J., Termotto V., Breuer J. Are Alzheimer patients healthier? J Am Geriatr Soc. 1988 Mar;36(3):219–224. doi: 10.1111/j.1532-5415.1988.tb01804.x. [DOI] [PubMed] [Google Scholar]

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