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. 1991 Jul;67(789):646–648. doi: 10.1136/pgmj.67.789.646

How reliable is the electrocardiogram in detecting left ventricular hypertrophy in hypertension?

S G Vijan 1, G Manning 1, M W Millar-Craig 1
PMCID: PMC2399080  PMID: 1833729

Abstract

This paper assesses the sensitivity and specificity of the electrocardiogram in detecting left ventricular hypertrophy in 75 hypertensive patients. Each patient underwent a 12 lead electrocardiogram and echocardiogram. Left ventricular mass index, using echocardiogram, was calculated according to the Penn convention and left ventricular hypertrophy was assessed by standard electrocardiographic criteria. The electrocardiogram was found to be very specific but insensitive in the detection of left ventricular hypertrophy as compared with the echocardiogram. Other non-voltage dependent markers appeared to have similar reliability. We conclude that the electrocardiogram may be unreliable in the detection of left ventricular hypertrophy in hypertensive patients. Accurate assessment of left ventricular hypertrophy, in these patients should be by echocardiography.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Antman E. M., Green L. H., Grossman W. Physiologic determinants of the electrocardiographic diagnosis of left ventricular hypertrophy. Circulation. 1979 Aug;60(2):386–396. doi: 10.1161/01.cir.60.2.386. [DOI] [PubMed] [Google Scholar]
  2. Bennett D. H., Evans D. W. Correlation of left ventricular mass determined by echocardiography with vectorcardiographic and electrocardiographic voltage measurements. Br Heart J. 1974 Oct;36(10):981–987. doi: 10.1136/hrt.36.10.981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Devereux R. B., Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. Circulation. 1977 Apr;55(4):613–618. doi: 10.1161/01.cir.55.4.613. [DOI] [PubMed] [Google Scholar]
  4. Hamer J., Shinebourne E., Fleming J. Significance of electrocardiographic changes in hypertension. Br Med J. 1969 Jan 11;1(5636):79–82. doi: 10.1136/bmj.1.5636.79. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Horton J. D., Sherber H. S., Lakatta E. G. Distance correction for precordial electrocardiographic voltage in estimating left ventricular mass: an echocardiographic study. Circulation. 1977 Mar;55(3):509–512. doi: 10.1161/01.cir.55.3.509. [DOI] [PubMed] [Google Scholar]
  6. Kannel W. B., Gordon T., Castelli W. P., Margolis J. R. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham study. Ann Intern Med. 1970 Jun;72(6):813–822. doi: 10.7326/0003-4819-72-6-813. [DOI] [PubMed] [Google Scholar]
  7. Levy D., Garrison R. J., Savage D. D., Kannel W. B., Castelli W. P. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990 May 31;322(22):1561–1566. doi: 10.1056/NEJM199005313222203. [DOI] [PubMed] [Google Scholar]
  8. Nixon J. V., Anderson R. J., Cohen M. L. Alterations in left ventricular mass and performance in patients treated effectively for thyrotoxicosis. A comparative echocardiographic study. Am J Med. 1979 Aug;67(2):268–276. doi: 10.1016/0002-9343(79)90402-9. [DOI] [PubMed] [Google Scholar]
  9. Reichek N., Devereux R. B. Left ventricular hypertrophy: relationship of anatomic, echocardiographic and electrocardiographic findings. Circulation. 1981 Jun;63(6):1391–1398. doi: 10.1161/01.cir.63.6.1391. [DOI] [PubMed] [Google Scholar]
  10. Romhilt D. W., Bove K. E., Norris R. J., Conyers E., Conradi S., Rowlands D. T., Scott R. C. A critical appraisal of the electrocardiographic criteria for the diagnosis of left ventricular hypertrophy. Circulation. 1969 Aug;40(2):185–195. doi: 10.1161/01.cir.40.2.185. [DOI] [PubMed] [Google Scholar]
  11. SOKOLOW M., LYON T. P. The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. Am Heart J. 1949 Feb;37(2):161–186. doi: 10.1016/0002-8703(49)90562-1. [DOI] [PubMed] [Google Scholar]
  12. Schulman S. P., Weiss J. L., Becker L. C., Gottlieb S. O., Woodruff K. M., Weisfeldt M. L., Gerstenblith G. The effects of antihypertensive therapy on left ventricular mass in elderly patients. N Engl J Med. 1990 May 10;322(19):1350–1356. doi: 10.1056/NEJM199005103221904. [DOI] [PubMed] [Google Scholar]

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