Abstract
Five patients with acute renal failure due to accelerated hypertension required regular dialysis treatment for 2-12 months (mean 8.8), before recovering sufficient renal function for dialysis to be withdrawn. Two patients who had prior evidence of chronic renal impairment remained off dialysis for 20 and 27 months before decompensating again to require regular dialysis treatment. Two patients with no prior history of renal disease have remained independent of dialysis for 32 and 48 months. The fifth patient was lost to follow-up after a 7 month dialysis-free period. Delayed recovery of renal function following accelerated hypertension is a distinct possibility and should be considered in such patients before contemplating long term strategies such as renal transplantation.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adelman R. D., Russo J. Malignant hypertension: recovery of renal function after treatment with antihypertensive medications and hemodialysis. J Pediatr. 1981 May;98(5):766–768. doi: 10.1016/s0022-3476(81)80840-2. [DOI] [PubMed] [Google Scholar]
- Amair P., Khanna R., Leibel B., Pierratos A., Vas S., Meema E., Blair G., Chisolm L., Vas M., Zingg W. Continuous ambulatory peritoneal dialysis in diabetics with end-stage renal disease. N Engl J Med. 1982 Mar 18;306(11):625–630. doi: 10.1056/NEJM198203183061101. [DOI] [PubMed] [Google Scholar]
- Atkinson A. B., Brown J. J., Lever A. F., Robertson J. I. Combined treatment of severe intractable hypertension with captopril and diuretic. Lancet. 1980 Jul 19;2(8186):105–108. doi: 10.1016/s0140-6736(80)90001-x. [DOI] [PubMed] [Google Scholar]
- Bacon B. R., Ricanati E. S. Severe and prolonged renal insufficiency. Reversal in a patient with malignant hypertension. JAMA. 1978 Mar 20;239(12):1159–1160. [PubMed] [Google Scholar]
- Bakir A. A., Bazilinski N., Dunea G. Transient and sustained recovery from renal shutdown in accelerated hypertension. Am J Med. 1986 Feb;80(2):172–176. doi: 10.1016/0002-9343(86)90005-7. [DOI] [PubMed] [Google Scholar]
- Barcenas C. G., Eigenbrodt E., Long D. L., Hull A. R. Recovery from malignant hypertension with anuria after prolonged hemodialysis. South Med J. 1976 Sep;69(9):1230–1233. doi: 10.1097/00007611-197609000-00039. [DOI] [PubMed] [Google Scholar]
- Bischel M. D., Gans D. S., Barbour B. H. Bilateral nephrectomy for hypertension. Ann Intern Med. 1972 Oct;77(4):656–658. doi: 10.7326/0003-4819-77-4-656. [DOI] [PubMed] [Google Scholar]
- Cordingley F. T., Jones N. F., Wing A. J., Hilton P. J. Reversible renal failure in malignant hypertension. Clin Nephrol. 1980 Aug;14(2):98–103. [PubMed] [Google Scholar]
- Eknoyan G., Siegel M. B. Recovery from anuria due to malignant hypertension. JAMA. 1971 Feb 15;215(7):1122–1125. [PubMed] [Google Scholar]
- Isles C. G., McLay A., Jones J. M. Recovery in malignant hypertension presenting as acute renal failure. Q J Med. 1984 Autumn;53(212):439–452. [PubMed] [Google Scholar]
- Luft F. C., Bloch R., Szwed J. J., Grim C. M., Grim C. E. Minoxidil treatment of malignant hypertension. Recovery of renal function. JAMA. 1978 Oct 27;240(18):1985–1987. [PubMed] [Google Scholar]
- Mamdani B. H., Lim V. S., Mahurkar S. D., Katz A. I., Dunea G. Recovery from prolonged renal failure in patients with accelerated hypertension. N Engl J Med. 1974 Dec 19;291(25):1343–1344. doi: 10.1056/NEJM197412192912509. [DOI] [PubMed] [Google Scholar]
- Milne F. J., James S. H., Veriava Y. Malignant hypertension and its renal complications in black South Africans. S Afr Med J. 1989 Aug 19;76(4):164–167. [PubMed] [Google Scholar]
- Mitchell H. C., Graham R. M., Pettinger W. A. Renal function during long-term treatment of hypertension with minoxidil: comparison of benign and malignant hypertension. Ann Intern Med. 1980 Nov;93(5):676–681. doi: 10.7326/0003-4819-93-5-676. [DOI] [PubMed] [Google Scholar]
- Sevitt L. H., Evans D. J., Wrong O. M. Acute oliguric renal failure due to accelerated (malignant) hypertension. Q J Med. 1971 Jan;40(157):127–144. [PubMed] [Google Scholar]
- Williams P. S., Fass G., Bone J. M. Renal pathology and proteinuria determine progression in untreated mild/moderate chronic renal failure. Q J Med. 1988 Apr;67(252):343–354. [PubMed] [Google Scholar]
