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. 1992 Mar;68(797):192–195. doi: 10.1136/pgmj.68.797.192

Adult metachromatic leukodystrophy with an unusual relapsing-remitting course.

M Sadeh 1, A Kuritzky 1, E Ben-David 1, Y Goldhammer 1
PMCID: PMC2399237  PMID: 1589377

Abstract

A 46 year old woman had a relapsing-remitting course of hemiparesis, disorientation, paraparesis and seizures, followed by progressive dementia, spasticity and ataxia. Computed tomography at onset showed a parietotemporal hypodense area with diffuse mottled enhancement obliterating the lateral ventricle. Subsequent scans demonstrated symmetric periventricular non-enhancing hypodensities, progressive ventricular enlargement and atrophy. Adult metachromatic leukodystrophy was diagnosed on the basis of low leukocyte arylsulphatase A level and metachromatic material accumulation at neural nerve biopsy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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