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. 1991 Apr;65(4):2141–2145. doi: 10.1128/jvi.65.4.2141-2145.1991

Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein.

M J Roth 1
PMCID: PMC240092  PMID: 2002557

Abstract

The integration protein (IN) is required for retrovirus DNA integration into the host DNA. The function of the C terminus of the Moloney murine leukemia virus IN protein was examined. The terminal 28 amino acids were found to be nonessential. A linker insertion at position 6025, within a 36-amino-acid insertion not found in any other retrovirus, also produced viable virus.

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Selected References

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