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. 1984 Jun;47(6):1238–1242. doi: 10.1128/aem.47.6.1238-1242.1984

Association of metal tolerance with multiple antibiotic resistance of bacteria isolated from drinking water.

J J Calomiris, J L Armstrong, R J Seidler
PMCID: PMC240203  PMID: 6742841

Abstract

Bacterial isolates from the drinking water system of an Oregon coastal community were examined to assess the association of metal tolerance with multiple antibiotic resistance. Positive correlations between tolerance to high levels of Cu2+, Pb2+, and Zn2+ and multiple antibiotic resistance were noted among bacteria from distribution waters but not among bacteria from raw waters. Tolerances to higher levels of Al3+ and Sn2+ were demonstrated more often by raw water isolates which were not typically multiple antibiotic resistant. A similar incidence of tolerance to Cd2+ was demonstrated by isolates of both water types and was not associated with multiple antibiotic resistance. These results suggest that simultaneous selection phenomena occurred in distribution water for bacteria which exhibited unique patterns of tolerance to Cu2+, Pb2+, and Zn2+ and antibiotic resistance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen D. A., Austin B., Colwell R. R. Antibiotic resistance patterns of metal-tolerant bacteria isolated from an estuary. Antimicrob Agents Chemother. 1977 Oct;12(4):545–547. doi: 10.1128/aac.12.4.545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Armstrong J. L., Calomiris J. J., Seidler R. J. Selection of antibiotic-resistant standard plate count bacteria during water treatment. Appl Environ Microbiol. 1982 Aug;44(2):308–316. doi: 10.1128/aem.44.2.308-316.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Armstrong J. L., Shigeno D. S., Calomiris J. J., Seidler R. J. Antibiotic-resistant bacteria in drinking water. Appl Environ Microbiol. 1981 Aug;42(2):277–283. doi: 10.1128/aem.42.2.277-283.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gardner P., Smith D. H. Studies on the epidemiology of resistance (R) factors. I. Analysis of Klebsiella isolates in a general hospital. II. A prospective study of R factor transfer in the host. Ann Intern Med. 1969 Jul;71(1):1–9. doi: 10.7326/0003-4819-71-1-1. [DOI] [PubMed] [Google Scholar]
  5. LeChevallier M. W., Seidler R. J., Evans T. M. Enumeration and characterization of standard plate count bacteria in chlorinated and raw water supplies. Appl Environ Microbiol. 1980 Nov;40(5):922–930. doi: 10.1128/aem.40.5.922-930.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lighthart B. Enrichment of cadmium-mediated antibiotic-resistant bacteria in a Douglas-fir (Pseudotsuga menziesii) litter microcosm. Appl Environ Microbiol. 1979 May;37(5):859–861. doi: 10.1128/aem.37.5.859-861.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Marques A. M., Congregado F., Simon-Pujol D. M. Antibiotic and heavy metal resistance of Pseudomonas aeruginosa isolated from soils. J Appl Bacteriol. 1979 Oct;47(2):347–350. doi: 10.1111/j.1365-2672.1979.tb01765.x. [DOI] [PubMed] [Google Scholar]
  8. McHugh G. L., Moellering R. C., Hopkins C. C., Swartz M. N. Salmonella typhimurium resistant to silver nitrate, chloramphenicol, and ampicillin. Lancet. 1975 Feb 1;1(7901):235–240. doi: 10.1016/s0140-6736(75)91138-1. [DOI] [PubMed] [Google Scholar]
  9. Nakahara H., Ishikawa T., Sarai Y., Kondo I. Distribution of resistances to metals and antibiotics of staphylococcal strains in Japan. Zentralbl Bakteriol Orig A. 1977 Apr;237(4):470–476. [PubMed] [Google Scholar]
  10. Nakahara H., Ishikawa T., Sarai Y., Kondo I. Frequency of heavy-metal resistance in bacteria from inpatients in Japan. Nature. 1977 Mar 10;266(5598):165–167. doi: 10.1038/266165a0. [DOI] [PubMed] [Google Scholar]
  11. Nakahara H., Ishikawa T., Sarai Y., Kondo I., Kozukue H., Silver S. Linkage of mercury, cadmium, and arsenate and drug resistance in clinical isolates of Pseudomonas aeruginosa. Appl Environ Microbiol. 1977 Apr;33(4):975–976. doi: 10.1128/aem.33.4.975-976.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Novick R. P., Roth C. Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. J Bacteriol. 1968 Apr;95(4):1335–1342. doi: 10.1128/jb.95.4.1335-1342.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Richmond M. H. Some environmental consequences of the use of antibiotics: or 'what goes up must come down'. J Appl Bacteriol. 1972 Jun;35(2):155–176. doi: 10.1111/j.1365-2672.1972.tb03687.x. [DOI] [PubMed] [Google Scholar]
  14. Ridgway H. F., Means E. G., Olson B. H. Iron bacteria in drinking-water distribution systems: elemental analysis of gallionella stalks, using x-ray energy-dispersive microanalysis. Appl Environ Microbiol. 1981 Jan;41(1):288–297. doi: 10.1128/aem.41.1.288-297.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Ridgway H. F., Olson B. H. Scanning electron microscope evidence for bacterial colonization of a drinking-water distribution system. Appl Environ Microbiol. 1981 Jan;41(1):274–287. doi: 10.1128/aem.41.1.274-287.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Suzuki S., Miyoshi Y., Nakaya R. R plasmids among Gram-negative bacteria with multiple drug resistance isolated in a general hospital. Microbiol Immunol. 1978;22(5):235–247. doi: 10.1111/j.1348-0421.1978.tb00369.x. [DOI] [PubMed] [Google Scholar]
  17. Timoney J. F., Port J., Giles J., Spanier J. Heavy-metal and antibiotic resistance in the bacterial flora of sediments of New York Bight. Appl Environ Microbiol. 1978 Sep;36(3):465–472. doi: 10.1128/aem.36.3.465-472.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Varma M. M., Thomas W. A., Prasad C. Resistance to inorganic salts and antibiotics among sewage-borne Enterobacteriaceae and Achromobacteriaceae. J Appl Bacteriol. 1976 Oct;41(2):347–349. doi: 10.1111/j.1365-2672.1976.tb00643.x. [DOI] [PubMed] [Google Scholar]

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