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. 1993 Apr;67(4):2355–2359. doi: 10.1128/jvi.67.4.2355-2359.1993

Different requirements for membrane fusion mediated by the envelopes of human immunodeficiency virus types 1 and 2.

T Dragic 1, M Alizon 1
PMCID: PMC240396  PMID: 8095307

Abstract

CD4+ cells derived from the human cell lines U87MG and SCL1 cannot be infected by human immunodeficiency virus type 1 (HIV-1) or fuse with cells expressing the HIV-1 envelope. This block was complemented in heterokaryons with HeLa cells and probably reflects the absence of cellular factors necessary for membrane fusion. Since U87MG cells expressing CD4 are permissive to HIV-2, distinct cellular factors could be required for fusion mediated by two related human retroviruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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