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. 1991 May;65(5):2686–2690. doi: 10.1128/jvi.65.5.2686-2690.1991

Immunologic priming with recombinant hepatitis A virus capsid proteins produced in Escherichia coli.

T F Powdrill 1, J M Johnston 1
PMCID: PMC240628  PMID: 1850041

Abstract

Hepatitis A virus capsid proteins (VP0, VP3, and VP1) have been synthesized in Escherichia coli for use in antigenic and immunogenic analyses. Rabbits immunized with each of these individual recombinant capsid proteins developed a rapid neutralizing antibody response when subsequently challenged with a subimmunogenic dose of whole virus.

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Selected References

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