Table 2.

Monotherapeutic effects of metformin and berberine

	Metformin (n=16)		Berberine (n=15)
	Baseline	End point	Baseline	End point
HbA1c (%)	9.15 ± 0.57	7.72 ± 0.43**	9.47 ± 0.65	7.48 ± 0.40**
FBG (mmol/L)	9.96 ± 0.64	7.16 ± 0.71**	10.63 ± 0.88	6.85 ± 0.53**
PBG (mmol/L)	20.53 ± 1.87	12.86 ± 0.77**	19.83 ± 1.66	11.05 ± 0.92**
Fasting insulin (μU/ml)	27.3 ± 4.4	22.9 ± 5.2	29.1 ± 5.3	24.0 ± 5.5
Postprandial insulin (μU/ml)	125.3 ± 29.8	110.5 ± 21.4	120.4 ± 31.4	116.0 ± 26.9
Triglyceride (mmol/L)	1.19 ± 0.12	1.17 ± 0.13	1.13 ± 0.13	0.89 ± 0.03*
Total cholesterol (mmol/L)	4.31 ± 0.28	4.27 ± 0.15	4.40 ± 0.21	3.83 ± 0.09*
HDL-C (mmol/L)	1.25 ± 0.06	1.31 ± 0.08	1.33 ± 0.10	1.22 ± 0.04
LDL-C (mmol/L)	2.55 ± 0.38	2.43 ± 0.11	2.47 ± 0.13	2.36 ± 0.06

Data are means ± SEM. Compared with baseline:

^*P<0.05,

^**P<0.01