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. 1992 May;66(5):3251–3256. doi: 10.1128/jvi.66.5.3251-3256.1992

Cytolytic T lymphocytes specific for tumors and infected cells from mice with a retrovirus-induced immunodeficiency syndrome.

J G Erbe 1, K A Green 1, K M Crassi 1, H C Morse 3rd 1, W R Green 1
PMCID: PMC241097  PMID: 1560546

Abstract

LP-BM5 retrovirus complex-infected C57BL/6 mice develop immunodeficiency, somewhat analogous to AIDS, termed murine AIDS (MAIDS). After secondary stimulation with syngeneic B-cell lymphomas from LP-BM5-infected mice, C57BL/6 mice produced vigorous CD8+ cytotoxic T lymphocytes specific for MAIDS-associated tumors. An anti-LP-BM5 specificity was suggested because spleen and lymph node cells from LP-BM5-infected mice served as target cells in competition assays, and cells from LP-BM5, but not ecotropic, virus-infected mice functioned as secondary in vitro stimulators to generate cytotoxic T lymphocytes to MAIDS tumors.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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