Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1983 May;59(691):315–316. doi: 10.1136/pgmj.59.691.315

A unique apudoma producing the glucagonoma and gastrinoma syndromes.

J Dawson, S R Bloom, R Cockel
PMCID: PMC2417425  PMID: 6878103

Abstract

A patient is described who presented with a 10 year history of intermittent peptic ulcer symptoms and a 3 year history of an undiagnosed skin rash. Investigations indicated raised plasma levels of gastrin, glucagon and pancreatic polypeptide. A single tumour was localised to the pancreas and resected. The tumour had the typical histology of an apudoma, and contained cells which stained for gastrin, glucagon, pancreatic polypeptide and neurotensin.

Full text

PDF
315

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bloom S. R., Adrian T. E., Polak J. M. Pancreatic polypeptide from pancreatic endocrine tumours. Lancet. 1980 Nov 8;2(8202):1026–1026. doi: 10.1016/s0140-6736(80)92179-0. [DOI] [PubMed] [Google Scholar]
  2. Broder L. E., Carter S. K. Pancreatic islet cell carcinoma. I. Clinical features of 52 patients. Ann Intern Med. 1973 Jul;79(1):101–107. doi: 10.7326/0003-4819-79-1-101. [DOI] [PubMed] [Google Scholar]
  3. Heitz P. U., Kasper M., Polak J. M., Klöppel G. Pathology of the endocrine pancreas. J Histochem Cytochem. 1979 Oct;27(10):1401–1402. doi: 10.1177/27.10.229158. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES